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USP-NF Online Release Notes

UPDATED: 29-April-2022

User Resources

USP-NF Online FAQs
USP-NF Reference Guideline
Official Text FAQs

Support for Internet Explorer 11 ending April 15, 2022

  • Microsoft has announced the end of support for the Internet Explorer 11 (IE11) web browser, and as a result, USP will no longer support the use of IE11 on all our online products as of April 15, 2022. Please note that this announcement does NOT mean that IE11 will no longer work with these products, but rather, future versions of our online products will no longer be tested on the IE11 browser, and some features may not work as expected. USP will support Microsoft Edge as a replacement for IE11 and will continue to support the use of Google Chrome with our online applications. Other browsers, such as Firefox and Safari, may also work with USP online products, but USP does not officially support those browsers, and some features may not work as expected.

New Enhancements for April 29, 2022

  • A previous USP–NF Online release included a new feature that showed official dates when hovering over revision highlighting within the Documentary Standard. This feature has been removed as of April 29, 2022.


  • If you saved a browser bookmark to a specific file in the USP-NF application prior to January 24, 2020,  you will need to update the browser bookmark as the URL has been updated slightly. This is the same for any link via email that you may have received prior to January 24, 2020. The link will no longer work after January 24, 2020. Bookmarks from within the application will still work as expected.
  • The following file displays complex official status due to complicated revision history:
    • Ziprasidone Capsules
    • Revision History:
      • Added in USP 40-NF 35 2S (To Be Official, December 1, 2017)
      • Revision Bulletin (Official Nov. 1, 2017, prior to USP 40-NF 35 2S file)
      • Revision Bulletin (Official May 1, 2018)
    • The "Currently Official" version is correct with the correct official date (Official as of 1-May-2018)
    • The official dates of the 'Older Versions' of this monograph should appear as follows:
      • USP 41-NF 36 – “Never Official”
      • USP 41-NF 36 1S – "No Longer Official, 1-Nov-2017 to 30-Apr-2018"
  • For files that have a USP41-NF36 revision that were superseded by an Accelerated Revision in the November, December, and January monthly posting, the entire document is currently official as of May 1, 2018. Any earlier official date that displays in the official status banner is based on the Accelerated Revision.
  • In the event that a "No Longer Official" version of a file displays a backwards date range (i.e., Official from 1-May-2018 to 30-Apr-2018) this version is to be considered "Never Official".
  • When viewing a file with a title change, two "Currently Official" versions will appear in the "Switch Version" drop down; switching between these versions in the drop down allows you to navigate between the two files.
  • Files with August 2017 and October 2017 Accelerated Revisions were included with the USP 41-NF 36 1S online publication, per the normal Accelerated Revision publishing schedule. These files, which were technically revised via Errata or Revision Bulletin, will not receive an Accelerated Revision icon as the online system views them as part of the USP 41-NF 36 1S online publication.
  • If a reagent title (or cross reference title) is not appearing in the navigation menu, please use the search function to find the reagent.
  • For the most accurate list of new and revised content in USP 41-NF 36, USP 41-NF 36 1S, USP 41-NF 36 2S, and USP 42-NF 37 please use the Annotated lists for those publications. There is a known issue with the New and Changed lists for these specific publications.
  • As of 1-Nov-2018, when accessing a file revised in First Supplement to USP 41-NF 36 you will be viewing a version of this document without the revision tagging. If you need access to a file with the revision tagging please access the First Supplement to USP 41-NF 36 in the legacy platform until December 1, 2018.
  • There is a known issue with the new search highlighting feature that does not work with our equation software. When searching for a title, if you encounter an equation that appears similar to the following, please navigate to that title from the main alphabetical Table of Contents.
  • release-note1.PNG


  • Fixed: UNII codes will appear as applicable in the generated PDFs associated with USP-NF, Issue 3 and future versions.
  • Fixed: We are aware of the following files that contain multiple revisions with differing official dates. Please access both the "Currently Official" and "To be Official" versions to see all currently official text.
    • Amlodipine and Atorvastatin Tablets
    • Colchicine
    • Miconazole Nitrate Topical Powder
    • Trazodone Hydrochloride Tablets
    • <724>
    • 0.01 M Sodium Thiosulfate VS


  • Fixed: From the dashboard, "Events and Training" is displaying links to out dated events.
  • Fixed: Some files may not show up in the "My Viewing Activity" located on the dashboard, however they can be bookmarked.
  • Fixed: The following 41 titles were not appearing in the USP 41-NF 36 1S and USP 41-NF 36 2S navigational Table of Contents from June 18, 2018 until June 29, 2018. All versions of these files with the correct official dates and statuses were available in the online product from the USP 41-NF 36 navigational table of contents and available via the search tool.
    •  <90>
    • <129>
    • <401>
    • <507>
    • <661.1>
    • <1197>
    • <1224>
    • <1225>
    • Acetazolamide Tablets
    • Acitretin Capsules
    • Aloe
    • Amlodipine and Benazepril Hydrochloride Capsules
    • Amlodipine Besylate Tablets
    • Buprenorphine Hydrochloride
    • Cabergoline Tablets
    • Candesartan Cilexetil and Hydrochlorothiazide Tablets
    • Chondroitin Sulfate Sodium, Shark
    • Dexamethasone Sodium Phosphate
    • Exenatide
    • Fluticasone Propionate Lotion
    • Hydrocodone Bitartrate
    • Hydroflumethiazide Tablets
    • Hydrogenated Castor Oil
    • Indomethacin Sodium
    • Insulin Glargine
    • Isoxsuprine Hydrochloride Injection
    • Meglumine
    • Methyldopa
    • Monoglyceride Citrate
    • Nimodipine
    • Ondansetron Orally Disintegrating Tablets
    • Pemetrexed Disodium
    • Pimozide Tablets
    • Polyoxyl 40 Hydrogenated Castor Oil
    • Potassium Citrate Extended-Release Tablets
    • Propafenone Hydrochloride Extended-Release Capsules
    • Quetiapine Tablets
    • Raloxifene Hydrochloride
    • Valsartan
    • Vinblastine Sulfate
  • Fixed: Hyperlinks referencing Chromatography <621>, Thin-Layer Chromatography are incorrectly linking to the USP Monograph Quinine Sulfate.
  • Fixed: There is a known issue with search results not returning documents with terms found only in the description section of classic format monographs.

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