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Accelerated Revisions by Official Date

Revision Bulletins are posted by the first of each month. Each Revision Bulletin includes the reason for the change and the complete Monograph or General Chapter Revision Bulletins are transferred to the Accelerated Revision History section when the standard is published and becomes official in the next USP–NF publication. For more information on the Revision Bulletins and the Accelerated Revision process, see USP's Guideline on the Use of Accelerated Processes for Revisions to USP–NF. See here for specific posting and official dates.

To view Revision Bulletins in alphabetical order please click here.

IRAs are published in Pharmacopeial Forum (PF) as proposed IRAs. After a 90-day notice and comment period and approval by the relevant USP Expert Committee, IRAs are posted as official text in this location of the USP website, and are incorporated into the next available official publication (USP–NF or Supplement) at which time the posting may also be found in the Accelerated Revision History. Official IRAs are no longer published in PF. The PF posting dates, comment deadlines and IRA posting and official dates are outlined here.

To view Interim Revision Announcements in alphabetical order, please click here.

Official May 2026

  • <665> Plastic Components and Systems Used to Manufacture Pharmaceutical Drug Products and Biopharmaceutical Drug Substances and Products Notice and Chapter (RB posted 29-Apr-2022; official 01-May-2026)

Official December 2025

  • <661.1> Plastic Materials of Construction Notice and Chapter (RB posted 27-Jan-2023; official 01-Dec-2025)

Official December 2023

  • <621> Chromatography Notice and Chapter (RB posted 28-Oct-2022; official 01-Dec-2023)
  • Enoxaparin Sodium (IRA posted 18-Nov-2022; official 01-Dec-2023)

Official November 2023

Official July 2023

  • <7> Labeling (IRA posted 31–Jul–2020; official 01–Sep–2023)

Official May 2023

  • Acyclovir Notice and Monograph (RB posted 29-Apr-2022; official 01-May-2023)
  • Magnesium Sulfate Notice and Monograph (RB posted 25–Feb–2022; official 01–May–2023)

Official March 2023

Official February 2023

  • Fosamprenavir Calcium Notice and Monograph (RB posted 27-Jan-2023; official 01-Feb-2023)

Official January 2023

  • Acetaminophen (IRA posted 18-Nov-2022; official 01-Jan-2023)
  • Amantadine Hydrochloride Tablets Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)
  • Ammonium Sulfate (IRA posted 18-Nov-2022; official 01-Jan-2023)
  • Maltose Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)
  • Mesalamine Extended-Release Capsules Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)
  • Nitrofurantoin Capsules Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)

Official December 2022

  • Esomeprazole Magnesium Notice and Monograph (RB posted 19-Dec-2022; official 20-Dec-2022)
  • Magnesia Tablets Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Carbonate Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Hydroxide Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Hydroxide Paste Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Oxide Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Trisilicate Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
  • Milk of Magnesia Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022) 

Official November 2022

Official October 2022

  • Acetaminophen Extended-Release Tablets Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
  • Lacosamide Tablets Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
  • Mesalamine Extended-Release Capsules Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
  • Nortriptyline Hydrochloride Capsules Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
  • Rifabutin Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)

Official September 2022 

Official August 2022

  • Calcipotriene Ointment Notice and Monograph (RB posted 29-Apr-2022; official 01-Aug-2022)
  • Fondaparinux Sodium Notice and Monograph (RB posted 29-Apr-2022; official 01-Aug-2022)

Official July 2022

  • Diatrizoate Meglumine and Diatrizoate Sodium Solution Notice and Monograph (RB posted 19-Jul-2022; official 20-Jul-2022)
  • Dextran 40 Notice and Monograph (RB posted 25–Mar–2022; official 01–Jul–2022)
  • Dextran 70 Notice and Monograph (RB posted 25–Mar–2022; official 01–Jul–2022)
  • Digoxin Tablets Notice and Monograph (RB posted 24-Jun-2022; official 01-Jul-2022)
  • Mexiletine Hydrochloride Capsules Notice and Monograph (RB posted 24-Jun-2022; official 01-Jul-2022)
  • Terazosin Capsules Notice and Monograph (RB posted 24-Jun-2022; official 01-Jul-2022)

Official June 2022

  • Levetiracetam Tablets Notice and Monograph (RB posted 15-Jun-2022; official 16-Jun-2022)
  • Azithromycin for Oral Suspension Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
  • Dextrose Injection Notice and Monograph (RB posted 29-Apr-2022; official 01-Jun-2022)
  • Diethylene Glycol Stearates Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
  • Hydroxychloroquine Sulfate Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
  • Levothyroxine Sodium Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
  • Loratadine Capsules Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
  • Methylprednisolone Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
  • Potassium Citrate Extended-Release Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)

Official May 2022

Official April 2022

  • Chlorzoxazone Tablets Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)
  • Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)
  • Metolazone Tablets Notice and Monograph (RB posted 14–Apr–2022; official 15–Apr–2022)
  • Nicardipine Hydrochloride Injection Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)
  • Oseltamivir Phosphate Capsules Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)

Official March 2022

  • Abacavir Oral Solution Notice and Monograph (RB posted 25–Feb–2022; official 01–Mar–2022)
  • Aripiprazole Tablets Notice and Monograph (RB posted 25–Feb–2022; official 01–Mar–2022)
  • Diclofenac Potassium for Oral Solution Notice and Monograph (posted 30–Mar–2022; official 31–Mar–2022)
  • Divalproex Sodium Extended-Release Tablets Notice and Monograph (RB posted 16–Mar–2022; official 17–Mar–2022)
  • Methotrexate (IRA posted 28–Jan–2022; official 01–Mar–2022)
  • Selenemethionine (IRA posted 28–Jan–2022; official 01–Mar–2022)

Official February 2022

  • Azeotropic Isopropyl Alcohol Notice and Monograph (RB posted 30–Jul–2021; official 01–Feb–2022)
  • Doxepin Hydrochloride Capsules Notice and Monograph (RB posted 28–Jan–2022; official 01–Feb–2022)
  • Isopropyl Alcohol Notice and Monograph (RB posted 30–Jul–2021; official 01–Feb–2022)
  • Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 28–Jan–2022; official 01–Feb–2022)
  • Nandrolone Decanoate Notice and Monograph Notice and Monograph (RB posted 28–Jan–2022; official 01–Feb–2022)

Official January 2022

Official December 2021

  • Baclofen Injection Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2021)
  • Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2021)
  • Quetiapine Extended-Release Tablets Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2021)
  • Starch TS Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2021)

Official November 2021

  • Acetaminophen Oral Suspension Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Alprazolam Tablets Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Amoxicillin Capsules Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Amoxicillin Tablets Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Bupropion Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021
  • Chlordiazepoxide Hydrochloride and Clidinium Bromide Capsules Notice and Monograph (RB posted 04–Nov–2021; official 05–Nov–2021)
  • Dexamethasone Tablets Notice and Monograph (RB posted 02–Nov–2021; official 03–Nov–2021)
  • Diphenhydramine Hydrochloride Capsules Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Diphenhydramine Hydrochloride Oral Solution Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Diphenhydramine and Phenylephrine Hydrochlorides Tablets Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Divalproex Sodium Delayed-Release Capsules Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Glycine Notice and Monograph (posted 29–Oct–2021; official 01–Nov–2021)
  • Phenylephrine Hydrochloride Tablets Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)
  • Rotigotine Notice and Monograph (RB posted 29–Oct–2021; official 01–Nov–2021)

Official October 2021

  • Quinidine Gluconate Extended-Release Tablets Notice and Monograph (RB posted 07–Oct–2021; official 08–Oct–2021)

Official September 2021

  • Mercaptopurine (IRA posted 30–Jul–2021; official 01–Sep–2021)
  • Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 16–Sep–2021; official 17–Sep–2021)
  • Quetiapine Extended-Release Tablets Notice and Monograph (RB posted 27–Aug–2021; official 01–Sep–2021)
  • Tranexamic Acid Tablets Notice and Monograph (RB posted 27–Aug–2021; official 01–Sep–2021)

Official August 2021

Official July 2021

  • Baclofen Injection Notice and Monograph (RB posted 25–Jun–2021; official 01–Jul–2021)
  • Benztropine Mesylate Notice and Monograph (RB posted 25–Jun–2021; official 01–Jul–2021) 
  • Budesonide Notice and Monograph (RB posted 25–Jun–2021; official 01–Jul–2021)
  • Oxcarbazepine Oral Suspension Notice and Monograph (RB posted 28–Jul–2021; official 29–Jul–2021)
  • Potassium Citrate Extended-Release Tablets Notice and Monograph (RB posted 25–Jun–2021; official 01–Jul–2021)

Official June 2021

  • (+)-1-(9-Fluoroenyl) ethyl Chloroformate Solution Reagent and Notice (RB posted 28–May–2021; official 01–Jun–2021) | En español
  • Buspirone Hydrochloride Tablets Monograph and Notice (RB posted 28–May–2021; official 01–Jun–2021) | En español
  • Chlorpromazine Hydrochloride Oral Concentrate Notice and Monograph (RB posted 14–Jun–2021; official 15–Jun–2021) 
  • Lovastatin Tablets Monograph and Notice (RB posted 28–May–2021; official 01–Jun–2021) | En español
  • Mesalamine Delayed-Release Tablets Monograph and Notice (RB posted 28–May–2021; official 01–Jun–2021) | En español
  • Nitrofurantoin Capsules Monograph and Notice (RB posted 28–May–2021; official 01–Jun–2021) | En español

Official May 2021

Official April 2021

Official March 2021

Official February 2021

Official January 2021

Official December 2020

Official November 2020

Official October 2020

Official September 2020

Official August 2020

Official July 2020

Official June 2020

Official May 2020

Official April 2020

Official March 2020

Official February 2020

Official January 2020

Revisions Official in 2019

    Revisions Official in 2018