After a standard is proposed in Pharmacopeial Forum (PF) for public comment, the assigned Expert Committee reviews the comments and determines whether to approve the standard as a Revision, defer or cancel the standard. USP posts the lists of Revisions, Deferrals, Cancellations, and Commentary for each Issue of USP–NF.
- Revisions are items that have been proposed in PF, were approved by the assigned Expert Committee, and will appear in the noted publication. These items will have corresponding Commentary (see below).
- Deferrals are items that have been proposed in PF but are not yet approved by an Expert Committee. Items that have been deferred can be approved and published in a subsequent Issue of USP–NF. Some deferrals are later canceled.
- Cancellations are items that have been proposed in PF but will not move forward to ballot and subsequent publication. Canceled items may be re-proposed in a future PF.
Commentary is a summary of comments received and the assigned Expert Committee's responses. Commentary is published for Revisions only. In cases where proposals have been re-published in PF, only comments from the most recent PF publication are included in Commentary. Revisions, Deferrals, and Cancellations generally are posted prior to publication in USP–NF Online. Commentary is posted the same day the official text is published in USP–NF Online.
Interim Revision Announcements
As of First Supplement to USP 43–NF 38, IRAs are no longer associated with a print publication and are immediately available on USP–NF Online.
IRAs published in 47(5)
- Carbidopa and Levodopa Tablets
- Loperamide Hydrochloride
IRAs published in 47(4)
- Ipratropium Bromide Inhalation Solution
- Orlistat Capsules
- Tetracycline Hydrochloride
- Tetracycline Hydrochloride Capsules
IRAs published in 47(3)
No new IRAs were published for comment in PF 47(3)
IRAs published in 47(2)
IRAs published in PF 47(1)
No new IRAs were published for comment in PF 47(1)
USP–NF 2022, Issue 1
USP–NF 2021, Issue 3
- Deferrals (posted 30–Apr–2021)
- Cancellations (posted 30–Apr–2021)
- Revisions (posted 30–Apr–2021)
- Commentary (posted 01–Jun–2021)
USP–NF 2021, Issue 2
- Deferrals (posted 28–Dec–2020; updated 29–Jan–2021)
- Cancellations (posted 28–Dec–2020)
- Revisions (posted 28–Dec–2020; updated 29–Jan–2021)
- Commentary (posted 01–Feb–2021)
USP–NF 2021, Issue 1
- Deferrals (posted 25–Sep–2020)
- Cancellations (posted 25–Sep–2020)
- Revisions (posted 25–Sep–2020)
- Commentary (posted 02–Nov–2020)
USP 43–NF 38
- Revisions (posted 24–Apr–2020)
- Deferrals (posted 24–Apr–2020)
- Cancellations (posted 24–Apr–2020)
- Commentary (posted 01–Jun–2020)
Due to the extended comment period for Pharmacopeial Forum 45(1), it will be included in the publication for Supplement 1 instead of that for USP–NF.
- Revisions (posted 26–Dec–2019)
- Deferrals (posted 26–Dec–2019)
- Cancellations (posted 26–Dec–2019)
- Commentary (posted 03–Feb–2020; revised 05–Feb–2020)
- Revisions (posted 26–Jul–2019)
- Deferrals (posted 26–Jul–2019)
- Cancellations (posted 26–Jul–2019)
- Commentary (posted 01–Nov–2019)
- Index (posted 01–Nov–2019)
IRAs published in 44(6)
- There were no IRAs published for comment in 44(6)