Interim Revision Announcements (IRAs)

IRAs are published in Pharmacopeial Forum (PF) as proposed IRAs. After a 90-day notice and comment period and approval by the relevant USP Expert Committee, IRAs are published as official text in the USP–NF Online. The PF posting dates, comment deadlines and IRA posting, and official dates can be found here. 

Monograph names listed prior to April 1, 2021 link to the combined IRA posting in which the announcement appeared. Titles posted after April 1, 2021 link to the published standard in USP–NF Online.

Archived Interim Revision Announcements can be found here.

New IRAs

• Carbidopa and Levodopa Tablets (posted 25–Mar–2022; official 01–May–2022)
• Paclitaxel (posted 25–Mar–2022; official 01–May–2022)
• Tetracycline (posted 25–Mar–2022; official 01–May–2022)
• Tetracycline Hydrochloride (posted 25–Mar–2022; official 01–May–2022)
• Tetracycline Hydrochloride Capsules (posted 25–Mar–2022; official 01–May–2022)
• Methotrexate (posted 28–Jan–2022; official 01–Mar–2022)
• Selenomethionine (posted 28–Jan–2022; official 01–Mar–2022)
• Ipratropium Bromide Inhalation Solution (posted 19–Nov–2021; official 01–Jan–2022)
• Orlistat (posted 19–Nov–2021; official 01–Jan–2022)
• Orlistat Capsules (posted 19–Nov–2021; official 01–Jan–2022)

All Posted IRAs

To view Accelerated Revisions by official date, please click here.

• <7> Labeling (posted 31–Jul–2020; official 01–Sep–2023)
• <467> Residual Solvents (posted 27–Sep–2019; official 01–Nov–2019) |En español
• Atropine Sulfate Ophthalmic Solution (posted 27–Sep–2019; official 01–Nov–2019) | En español
• Carbidopa and Levodopa Tablets (posted 25–Mar–2022; official 01–May–2022)
• Cetyl Alcohol (posted 25–Sep–2020; official 01–Nov–2020) | En español
• Desmopressin Acetate (posted 29–Jan–2021; official 01–Mar–2021) | En español
• Diethyl Sebacate (posted 26–Jan–2018; official 01–Mar–2018)
• Filgrastim (posted 20–Nov–2020; official 01–Jan–2021) | En español
• Formoterol Fumarate (posted 22-–Nov–2019; official 01–Jan–2020) | En español
• Gemfibrozil Tablets (posted 26–Mar–2021; official May 1, 2021)
• Goserelin Acetate (posted 27–Mar–2020; official 01–May–2020)
• Human Insulin Isophane Suspension and Human Insulin Injection (posted 30–Nov–2018; official 01–Jan– 2019) | En español
• Insulin (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Insulin Aspart Injection (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Insulin Injection (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Insulin Lispro (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Insulin Lispro Injection (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Insulin Zinc Suspension (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Ioversol (posted 26–Mar–2021; official May 1, 2021)
• Ioversol Injection (posted 26–Mar–2021; official May 1, 2021)
• Ipratropium Bromide Inhalation Solution (posted 19–Nov–2021; official 01–Jan–2022)
• Isophane Insulin Human Suspension (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Isophane Insulin Suspension (posted 30–Nov–2018; official 01–Jan–2019) | En español
• Levothyroxine Sodium (posted 26–Jul–2019; official 01–Sep–2019) | En español
• Medium Chain Triglycerides (posted 25–Jan–2019; official 01–Mar–2019) | En español
• Mercaptopurine (published 30–Jul–2021)
• Methotrexate (posted 28–Jan–2022; official 01–Mar–2022)
• Morphine Sulfate Compounded Injection (posted 26–Jul–2019; official 01–Sep–2019) | En español
• Orlistat (posted 19–Nov–2021; official 01–Jan–2022)
• Orlistat Capsules (posted 19–Nov–2021; official 01–Jan–2022)
• Paclitaxel (posted 25–Mar–2022; official 01–May–2022)
• Paroxetine Hydrochloride (posted 26–Mar–2021; official May 1, 2021)
• Ribose (posted 29–Jan–2021; official 01–Mar–2021) | En español
• Selenemethionine (posted 28–Jan–2022; official 01–Mar–2022)
• Stearyl Alcohol (posted 25–Sep–2020; official 01–Nov–2020) | En español
• Sulfamethoxazole (posted 26–Mar–2021; official May 1, 2021)
• Telmisartan and Amlodipine Tablets (posted 25–Sep–2020; official 01–Dec–2020) | En español
• Temozolomide (posted 31–Jul–2020; official 01–Mar–2021)
• Temozolomide Capsules (posted 31–Jul–2020; official 01–Mar–2021)
• Temozolomide for Injection (posted 31–Jul–2020; official 01–Mar–2021)
• Tetracycline (posted 25–Mar–2022; official 01–May–2022)
• Tetracycline Hydrochloride (posted 25–Mar–2022; official 01–May–2022)
• Tetracycline Hydrochloride Capsules (posted 25–Mar–2022; official 01–May–2022)
• Travoprost Ophthalmic Solution (posted 31–Jul–2020; official 01–Sep–2020)
• Triamcinolone Acetonide Nasal Spray (posted 29–Jan–2021; official 01–Mar–2021) | En español
• Zolmitriptan (posted 27–Mar–2020; official 01–May–2020)