Accelerated Revisions by Official Date

Revision Bulletins are posted by the first of each month. Each Revision Bulletin includes the reason for the change and the complete Monograph or General Chapter Revision Bulletins are transferred to the Accelerated Revision History section when the standard is published and becomes official in the next USP–NF publication. For more information on the Revision Bulletins and the Accelerated Revision process, see USP's Guideline on the Use of Accelerated Processes for Revisions to USP–NF. See here for specific posting and official dates.

To view Revision Bulletins in alphabetical order please click here.

IRAs are published in Pharmacopeial Forum (PF) as proposed IRAs. After a 90-day notice and comment period and approval by the relevant USP Expert Committee, IRAs are posted in USP-NF Online and moved to the Accelerated Revision History page approximately one year after becoming official.. The PF posting dates, comment deadlines and IRA posting and official dates are outlined here.

To view Interim Revision Announcements in alphabetical order, please click here.

Official May 2026

<665> Plastic Components and Systems Used to Manufacture Pharmaceutical Drug Products and Biopharmaceutical Drug Substances and Products Notice and Chapter (RB posted 29-Apr-2022; official 01-May-2026)

Official December 2025

<661.1> Plastic Materials of Construction Notice and Chapter (RB posted 27-Jan-2023; official 01-Dec-2025)

Official December 2023

<621> Chromatography Notice and Chapter (RB posted 28-Oct-2022; official 01-Dec-2023)
Enoxaparin Sodium (IRA posted 18-Nov-2022; official 01-Dec-2023)

Official November 2023

Albuterol Inhalation Solution Notice and Monograph (RB posted 30–Apr–2021; official 01–Nov–2023)

Official August 2023

Nitrofurantoin Capsules Notice and Monograph (RB posted 28-Apr-2023; official 01-Aug-2023)

Official July 2023

<7> Labeling (IRA posted 31–Jul–2020; official 01–Sep–2023)
Ziprasidone Hydrochloride (IRA posted 26-May-2023; official 01-Jul-2023)

Official June 2023

Isosorbide Dinitrate Tablets Notice and Monograph (RB posted 26-May-2023; official 01-Jun-2023)
Sodium Bicarbonate Notice and Monograph (RB posted 26-May-2023; official 01-Jun-2023)
Sorafenib Tablets Notice and Monograph (RB posted 26-May-2023; official 01-Jun-2023)
Sucrose Notice and Monograph (RB posted 26-May-2023; official 01-Jun-2023)

Official May 2023

<711> Dissolution (IRA posted 31-Mar-2023; official 01-May-2023)
Acyclovir Notice and Monograph (RB posted 29-Apr-2022; official 01-May-2023)
Diltiazem Hydrochloride Extended-Release Capsules Notice and Monograph (posted 28-Apr-2023; official 01-May-2023)
Magnesium Sulfate Notice and Monograph (RB posted 25–Feb–2022; official 01–May–2023)
Phenelzine Sulfate (IRA posted 31-Mar-2023; official 01-May-2023)
Urea C-13 (IRA posted 31-Mar-2023; official 01-May-2023)
Vigabatrin Tablets Notice and Monograph (RB posted 28-Apr-2023; official 01-May-2023)

Official April 2023

<621> Chromatography Notice and Chapter (RB posted 31-Mar-2023; official 01-Apr-2023)
Anticoagulant Citrate Phosphate Dextrose Adenine Solution Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Anticoagulant Heparin Solution Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Antithrombin III Human Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Caffeine Citrate Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Carbamazepine Extended-Release Tablets Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Colchicine Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Estradiol and Norethindrone Acetate Tablets Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Etoposide Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Fluphenazine Decanoate Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Fondaparinux Sodium Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Furosemide Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Iodixanol Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Iohexol Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Iron Sucrose Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Ranitidine Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Sodium Thiosulfate Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Tylosin Injection Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)
Vigabatrin Tablets Notice and Monograph (RB posted 31-Mar-2023; official 01-Apr-2023)

Official March 2023

Doxepin Hydrochloride Capsules Notice and Monograph (RB posted 24-Feb-2023; official 01-Mar-2023)
Fluoxetine Capsules Notice and Monograph (RB posted 24-Feb-2023; official 01-Mar-2023)
Isotretinoin Capsules (IRA posted 27-Jan-2023; official 01-Mar-2023)

Official February 2023

Fosamprenavir Calcium Notice and Monograph (RB posted 27-Jan-2023; official 01-Feb-2023)
Minocycline Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 16-Feb-2023; official 17-Feb-2023)

Official January 2023

Acetaminophen (IRA posted 18-Nov-2022; official 01-Jan-2023)
Amantadine Hydrochloride Tablets Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)
Ammonium Sulfate (IRA posted 18-Nov-2022; official 01-Jan-2023)
Maltose Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)
Mesalamine Extended-Release Capsules Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)
Nitrofurantoin Capsules Notice and Monograph (RB posted 16-Dec-2022; official 01-Jan-2023)

Official December 2022

Esomeprazole Magnesium Notice and Monograph (RB posted 19-Dec-2022; official 20-Dec-2022)
Magnesia Tablets Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
Magnesium Carbonate Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
Magnesium Hydroxide Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
Magnesium Hydroxide Paste Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
Magnesium Oxide Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
Magnesium Trisilicate Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)
Milk of Magnesia Notice and Monograph (RB posted 19–Nov–2021; official 01–Dec–2022)

Official November 2022

Tobramycin Sulfate Notice and Monograph (RB posted 08-Nov-2022; official 09-Nov-2022)
<209> Low Molecular Weight Heparin Molecular Weight Determinations (IRA posted 30-Sep-2022; official 01-Nov-2022)
<411> Folic Acid Assay (IRA posted 30-Sep-2022; official 01-Nov-2022)
Doxycycline Hyclate Tablets Notice and Monograph (RB posted 08-Nov-2022; official 09-Nov-2022)
Folic Acid Tablets (IRA posted 30-Sep-2022; official 01-Nov-2022)
Levalbuterol Hydrochloride (IRA posted 30-Sep-2022; official 01-Nov-2022)
Levalbuterol Inhalation Solution (IRA posted 30-Sep-2022; official 01-Nov-2022)
Metoprolol Succinate Extended-Release Tablets Notice and Monograph (RB posted 02-Nov-2022; official 03-Nov-2022)
Tacrolimus Capsules Notice and Monograph (RB posted 02-Nov-2022; official 03-Nov-2022)
Carbidopa and Levodopa Tablets Notice and Monograph (RB posted 28-Oct-2022; official 01-Nov-2022)
Guanfacine Extended-Release Tablets Notice and Monograph (RB posted 28-Oct-2022; official 01-Nov-2022)
Lamotrigine Extended Release Tablets Notice and Monograph (RB posted 28-Oct-2022; official 01-Nov-2022)

Official October 2022

Acetaminophen Extended-Release Tablets Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
Lacosamide Tablets Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
Mesalamine Extended-Release Capsules Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
Nortriptyline Hydrochloride Capsules Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)
Rifabutin Notice and Monograph (RB posted 30-Sep-2022; official 01-Oct-2022)

Official September 2022

Carbamazepine Tablets Notice and Monograph (RB posted 21-Sep-2022; official 22-Sep-2022)
Rufinamide Tablets Notice and Monograph (posted 15-Sep-2022; official 16-Sep-2022)
Prochlorperazine Maleate Tablets Notice and Monograph (posted 06-Sep-2022; official 07-Sep-2022)
<89.2> Collagenase II (IRA posted 29-Jul-2022; official 01-Sep-2022)
Fluticasone Propionate Inhalation Aerosol (IRA posted 29-Jul-2022; official 01-Sep-2022)
Fluticasone Propionate Inhalation Powder (IRA posted 29-Jul-2022; official 01-Sep-2022)
Fluticasone Propionate and Salmeterol Inhalation Powder (IRA posted 29-Jul-2022; official 01-Sep-2022)
Mesalamine Delayed-Release Tablets (IRA posted 29-Jul-2022; official 01-Sep-2022)
Salmeterol Inhalation Powder (IRA posted 29-Jul-2022; official 01-Sep-2022)
Temozolomide Capsules Notice and Monograph (RB posted 26-Aug-2022; official 01-Sep-2022)
Venlafaxine Hydrochloride Extended-Release Capsules Notice and Monograph (posted 26-Aug-2022; official 01-Sep-2022)

Official August 2022

Calcipotriene Ointment Notice and Monograph (RB posted 29-Apr-2022; official 01-Aug-2022)
Fondaparinux Sodium Notice and Monograph (RB posted 29-Apr-2022; official 01-Aug-2022)

Official July 2022

Diatrizoate Meglumine and Diatrizoate Sodium Solution Notice and Monograph (RB posted 19-Jul-2022; official 20-Jul-2022)
Dextran 40 Notice and Monograph (RB posted 25–Mar–2022; official 01–Jul–2022)
Dextran 70 Notice and Monograph (RB posted 25–Mar–2022; official 01–Jul–2022)
Digoxin Tablets Notice and Monograph (RB posted 24-Jun-2022; official 01-Jul-2022)
Mexiletine Hydrochloride Capsules Notice and Monograph (RB posted 24-Jun-2022; official 01-Jul-2022)
Terazosin Capsules Notice and Monograph (RB posted 24-Jun-2022; official 01-Jul-2022)

Official June 2022

Levetiracetam Tablets Notice and Monograph (RB posted 15-Jun-2022; official 16-Jun-2022)
Azithromycin for Oral Suspension Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
Dextrose Injection Notice and Monograph (RB posted 29-Apr-2022; official 01-Jun-2022)
Diethylene Glycol Stearates Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
Hydroxychloroquine Sulfate Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
Levothyroxine Sodium Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
Loratadine Capsules Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
Methylprednisolone Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)
Potassium Citrate Extended-Release Tablets Notice and Monograph (RB posted 27–May–2022; official 01–Jun–2022)

Official May 2022

Abiraterone Acetate Tablets Notice and Monograph (RB posted 04–May–2022; official 05–May–2022)
Carbidopa and Levodopa Orally Disintegrating Tablets Notice and Monograph (RB posted 29-Apr-2022; official 01-May-2022)
Carbidopa and Levodopa Tablets (IRA posted 25–Mar–2022; official 01–May–2022)
Methylprednisolone Sodium Succinate for Injection Notice and Monograph (RB posted 04–May–2022; official 05–May–2022)
Paclitaxel (IRA posted 25–Mar–2022; official 01–May–2022)
Tetracycline (IRA posted 25–Mar–2022; official 01–May–2022)
Tetracycline Hydrochloride (IRA posted 25–Mar–2022; official 01–May–2022)
Tetracycline Hydrochloride Capsules (IRA posted 25–Mar–2022; official 01–May–2022)
Vancomycin Injection Notice and Monograph (posted 29-Apr-2022; official 01-May-2022)

Official April 2022

Chlorzoxazone Tablets Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)
Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)
Metolazone Tablets Notice and Monograph (RB posted 14–Apr–2022; official 15–Apr–2022)
Nicardipine Hydrochloride Injection Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)
Oseltamivir Phosphate Capsules Notice and Monograph (RB posted 25–Mar–2022; official 01–Apr–2022)

Official March 2022

Abacavir Oral Solution Notice and Monograph (RB posted 25–Feb–2022; official 01–Mar–2022)
Aripiprazole Tablets Notice and Monograph (RB posted 25–Feb–2022; official 01–Mar–2022)
Diclofenac Potassium for Oral Solution Notice and Monograph (posted 30–Mar–2022; official 31–Mar–2022)
Divalproex Sodium Extended-Release Tablets Notice and Monograph (RB posted 16–Mar–2022; official 17–Mar–2022)
Methotrexate (IRA posted 28–Jan–2022; official 01–Mar–2022)
Selenemethionine (IRA posted 28–Jan–2022; official 01–Mar–2022)

Official February 2022

Azeotropic Isopropyl Alcohol Notice and Monograph (RB posted 30–Jul–2021; official 01–Feb–2022)
Doxepin Hydrochloride Capsules Notice and Monograph (RB posted 28–Jan–2022; official 01–Feb–2022)
Isopropyl Alcohol Notice and Monograph (RB posted 30–Jul–2021; official 01–Feb–2022)
Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 28–Jan–2022; official 01–Feb–2022)
Nandrolone Decanoate Notice and Monograph Notice and Monograph (RB posted 28–Jan–2022; official 01–Feb–2022)

Official January 2022

Desipramine Hydrochloride Tablets Notice and Monograph (RB posted 31–Dec–2021; official 01–Jan–2022)
Ipratropium Bromide Inhalation Solution (IRA posted 19–Nov–2021; official 01–Jan–2022)
Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (RB posted 06–Jan–2022; official 07–Jan–2022)
Orlistat (IRA posted 19–Nov–2021; official 01–Jan–2022)
Orlistat Capsules (IRA posted 19–Nov–2021; official 01–Jan–2022)

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