Revision Bulletins are posted by the first of each month. Each Revision Bulletin includes the reason for the change and the complete Monograph or General Chapter Revision Bulletins are transferred to the Accelerated Revision History section when the standard is published and becomes official in the next USP–NF book or Supplement. For more information on the Revision Bulletins and the Accelerated Revision process, see USP's Guideline on the Use of Accelerated Processes for Revisions to USP–NF. See the chart below for specific posting and official dates.
|
Month |
Online Posting Date |
Official Dates for Compliance-related Revision Bulletins |
Official Dates for All* Other Revision Bulletins *unless otherwise indicated |
Incorporated into Print Publication |
|---|---|---|---|---|
| September 2019 | September 27, 2019 | October 1, 2019 | November 1, 2019 | N/A |
| October 2019 | October 25, 2019 | November 1, 2019 | December 1, 2019 | N/A |
| November 2019 | November 22, 2019 | December 1, 2019 | January 1, 2020 | N/A |
| December 2019 | December 27, 2019 | January 1, 2020 | February 1, 2020 | N/A |
| January 2020 | January 24, 2020 | February 1, 2020 | March 1, 2020 | N/A |
| February 2020 | February 28, 2020 | March 1, 2020 | April 1, 2020 | N/A |
| March 2020 | March 27, 2020 | April 1, 2020 | May 1, 2020 | N/A |
| April 2020 | April 24, 2020 | May 1, 2020 | June 1, 2020 | N/A |
| May 2020 | May 29, 2020 | June 1, 2020 | July 1, 2020 | N/A |
| June 2020 | June 26, 2020 | July 1, 2020 | August 1, 2020 | N/A |
| July 2020 | July 31, 2020 | August 1, 2020 | September 1, 2020 | N/A |
| August 2020 | August 28, 2020 | September 1, 2020 | October 1, 2020 | N/A |
| September 2020 | September 25, 2020 | October 1, 2020 | November 1, 2020 | N/A |
IRAs are published in Pharmacopeial Forum (PF) as proposed IRAs. After a 90-day notice and comment period and approval by the relevant USP Expert Committee, IRAs are posted as official text in this location of the USP website, and are incorporated into the next available official publication (USP–NF or Supplement) at which time the posting may also be found in the Accelerated Revision History. Official IRAs are no longer published in PF. The PF posting dates, comment deadlines and IRA posting and official dates are outlined in the chart below.
|
PF |
Proposed IRA Posting |
Public Comment Due Date |
Final IRA Posting Date on Web and USPNF.com |
Incorporated into Print Publication |
IRA Official Date |
|---|---|---|---|---|---|
| 45(3) | May 1, 2019 | Jul. 31, 2019 | Sep. 27, 2019 | N/A | Nov. 1, 2019 |
| 45(4) | Jul. 1, 2019 | Sep. 30, 2019 | Nov. 30, 2019 | N/A | Jan. 1, 2020 |
| 45(5) | Sep. 1, 2019 | Nov. 30, 2019 | Jan. 31, 2020 | N/A | Mar, 1, 2020 |
| 45(6) | Nov. 1, 2019 | Jan. 1, 2020 | Mar. 27, 2020 | N/A | May 1, 2020 |
| 46(1) | Jan. 2, 2020 | March 31, 2020 | May 29, 2020 | N/A | July 1, 2020 |
| 46(2) | Mar. 1, 2020 | May 31, 2020 | July 31, 2020 | N/A | Sept. 1, 2020 |
* Comment date extended. Please see this Notice for more information.
To view Interim Revision Announcements in alphabetical order, please click here.
To view Revision Bulletins in alphabetical order please click here.
Official December 2019
- <800> Hazardous Drugs—Handling in Healthcare Settings (RB posted 31–May–2019, updated 27–Sep–2019; official 01–Dec–2019)
- Amiodarone Hydrochloride Tablets (RB posted 25–Oct–2019; official 01–Dec–2019)
Official November 2019
- <467> Residual Solvents (IRA posted 27–Sep–2019; official 01–Nov–2019)
- Atropine Sulfate Ophthalmic Solution (IRA posted 27–Sep–2019; official 01–Nov–2019)
- Cyclophosphamide for Injection (RB posted 25–Oct–2019; official 01–Nov–2019)
- Tadalafil Tablets (RB posted 25–Oct–2019; official 01–Nov–2019)
Official October 2019
- Isosorbide Mononitrate Extended-Release Tablets (RB posted 27–Sep–2019; official 01–Oct–2019)
- Levothyroxine Sodium Tablets (RB posted 27–Sep–2019; official 01–Oct–2019)
- Oxybutynin Chloride Extended-Release Tablets (RB posted 27–Sep–2019; official 01–Oct–2019)
- Ziprasidone Capsules (RB posted 27–Sep–2019; official 01–Oct–2019)
Official September 2019
- <7> Labeling (RB posted 30–Aug–2019; official 01–Sep–2019)
- Levothyroxine Sodium (IRA posted 26–Jul–2019; official 01–Sep–2019)
- Morphine Sulfate Compounded Injection (IRA posted 26–Jul–2019; official 01–Sep–2019)
- Olmesartan Medoxomil Tablets (RB posted 30–Aug–2019; official 01–Sep–2019)
- Potassium Chloride Extended-Release Tablets (posted 30–Aug–2019; official 01–Sep–2019)
Official August 2019
- Esomeprazole Magnesium Delayed-Release Capsules (RB posted 26–Jul–2019; official 01–Aug–2019)
- Iohexol (RB posted 26–Jul–2019; official 01–Aug–2019)
- Itraconazole Capsules (RB posted 31–May–2019; official 01–Aug–2019)
- Manganese Sulfate Injection (RB posted 26–Jul–2019; official 01–Aug–2019)
- Methylphenidate Hydrochloride Extended-Release Tablets (RB posted 26–Jul–2019; official 01–Aug–2019)
- Potassium Chloride Extended-Release Tablets (posted 20–Aug–2019; official 21–Aug–2019)
- Potassium Chloride Extended-Release Tablets (posted 31–Jul–2019; official 01–Aug–2019)
- Tranexamic Acid Tablets (RB posted 26–Jul–2019; official 01–Aug–2019)
Official July 2019
- Ropinirole Extended-Release Tablets (RB posted 28–Jun–2019; official 01–Jul–2019)
- Erythromycin Delayed-Release Tablets (RB posted 24–Jul–2019; official 25–Jul–2019)
Official June 2019
- Cidovovir (RB posted 31–May–2019; official 01–Jun–2019)
- Clonidine Transdermal System (RB posted 31–May–2019; official 01–Jun–2019)
- Penicillamine Capsules (RB posted 10–Jun–2019; official 11–Jun–2019)
Official May 2019
- <7> Labeling (RB posted 26–Apr–2019; official 01–May–2019)
- <121> Insulin Assays (RB posted 29–Mar–2019; official 01–May–2019)
- Calcium Acetate Capsules (RB posted 26–Apr–2019; official 01–May–2019)
- Diltiazem Hydrochloride Extended-Release Capsules (RB posted 26–Apr–2019; official 01–May–2019)
- Extended Insulin Zinc Suspension (RB posted 29–Mar–2019; official 01–May–2019)
- Fenofibrate Capsules (RB posted 26–Apr–2019; official 01–May–2019)
- Insulin (RB posted 29–Mar–2019; official 01–May–2019)
- Insulin Zinc Suspension (RB posted 29–Mar–2019; official 01–May–2019)
- Isophane Insulin Suspension (RB posted 29–Mar–2019; official 01–May–2019)
- Methotrexate Injection (RB posted 26–Apr–2019; official 01–May–2019)
- Miconazole Nitrate (RB posted 26–Apr–2019; official 01–May–2019)
- Pantoprazole Sodium Delayed-Release Tablets (RB posted 26–Apr–2019; official 01–May–2019)
- Prompt Insulin Zinc Suspension (RB posted 29–Mar–2019; official 01–May–2019)
- Triamcinolone Acetonide Nasal Spray (RB posted 25–Jan–2019; official 01–May–2019)
Official April 2019
- Drospirenone and Ethinyl Estradiol Tablets (RB posted 29–Mar–2019; official 01–Apr–2019)
- Quetiapine Extended-Release Tablets (posted 29–Mar–2019; official 01–Apr–2019)
- Rosuvastatin Tablets (posted 29–Mar–2019; official 01–Apr–2019)
Official March 2019
- <1099> Limit on Number of Large Deviations When Assessing Content Uniformity in Large Samples- Postponement (RB posted 22–Feb–2019; official 01–Mar–2019)
- Alprazolam Tablets (RB posted 22–Feb–2019; official 01–Mar–2019)
- Bendamustine Hydrochloride (RB posted 22–Feb–2019; official 01–Mar–2019)
- Donepezil Hydrochloride Tablets (RB posted 22–Feb–2019; official 01–Mar–2019)
- Medium Chain Triglycerides (IRA posted 25–Jan–2019; official 01–Mar–2019)
- Metformin Hydrochloride Extended-Release Tablets (RB posted 22–Feb–2019; official 01–Mar–2019)
- Olmesartan Medoxomil Tablets (posted 18–Mar–2019; official 19–Mar–2019)
- Naproxen Sodium and Pseudoephedrine Hydrochloride Extended-Release Tablets (RB posted 22–Feb–2019; official 01–Mar–2019)
- Propafenone Hydrochloride Extended-Release Capsules (RB posted 07–Mar–2019; official 08–Mar–2019)
- Psuedoephedrine Hydrochloride Extended-Release Tablets (RB posted 22–Feb–2019; official 01–Mar–2019)
- Taurine (RB posted 22–Feb–2019; official 01–Mar–2019)
- Vancomycin Injection (RB posted 28–Feb–2019; official 01–Mar–2019)
Official February 2019
- Atorvastatin Calcium Tablets (RB posted 25–Jan–2019; official 01–Feb–2019)
- Benzethonium Chloride (RB posted 25–Jan–2019; official 01–Feb–2019)
- Bupropion Hydrochloride Extended-Release Tablets (RB posted 25–Jan–2019; official 01–Feb–2019)
- Glucagon for Injection (RB posted 25–Jan–2019; official 01–Feb–2019)
- Lamotrigine Extended-Release Tablets (RB posted 25–Jan–2019; official 01–Feb–2019)
- Telimisartan and Amlodipine Tablets (RB posted 25–Jan–2019; official 01–Feb–2019)
Official January 2019
- Human Insulin Isophane Suspension and Human Insulin Injection (IRA posted 30–Nov–2018; official 01–Jan– 2019)
- Insulin Aspart Injection (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Insulin Injection (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Insulin (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Insulin Lispro Injection (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Insulin Lispro (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Insulin Zinc Suspension (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Isophane Insulin Human Suspension (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Isophane Insulin Suspension (IRA posted 30–Nov–2018; official 01–Jan–2019)
- Nitrofurantoin Capsules (RB posted 28–Dec–2018; official 01–Jan–2019)
- Quetiapine Extended-Release Tablets (RB posted 28–Dec–2018; official 01–Jan–2019)
Official December 2018
- Desloratadine Orally Disintegrating Tablets (RB posted 30–Nov–2018; official 01–Dec–2018)
- Drosperinone and Ethinyl Estradiol Tablets (RB posted 30–Nov–2018; official 01–Dec–2018)
- Metoprolol Succinate Extended-Release Tablets (RB posted 30–Nov–2018; official 01–Dec–2018)
Official November 2018
- Bicalutamide Tablets (RB posted 26–Oct–2018; official 01–Nov–2018)
- Doxycycline Hyclate Tablets (RB posted 26–Oct–2018; official 01–Nov–2018)
- Fexofenadine Hydrochloride Tablets (RB posted 20–Oct–2018; official 01–Nov–2018)
- Morphine Sulfate Extended-Release Capsules (RB posted 26–Oct–2018; official 01–Nov–2018)
- Olmesartan Medoxomil Tablets (RB posted 26–Oct–2018; official 01–Nov–2018)
- Telmisartan and Amlodipine Tablets (RB posted 26–Oct–2018; official 01–Nov–2018)
Official October 2018
- Isosorbide Mononitrate Extended-Release Tablets (RB posted 05–Oct–2018; official 08–Oct–2018)
- Prasugrel Hydrochloride (RB posted 28–Sep–2018; official 01–Oct–2018)
Official September 2018
- Metformin Hydrochloride Extended-Release Tablets (RB posted 21–Sep–2018; official 24–Sep–2018)
- Potassium Chloride Extended-Release Capsules (RB posted 31–Aug–2018; official 01–Sep–2018)
- Potassium Chloride Extended-Release Tablets (RB posted 31–Aug–2018; official 01–Sep–2018)
Official August 2018
- Acetaminophen Oral Suspension (Postponement) (RB posted 27–Jul–2018; official 01–Aug–2018)
- Fexofenadine Hydrochloride and Pseudoephedrine Extended-Release Tablets (RB posted 29–Jun–2018; official 01–Jul–2018; updated 27–Jul–2018; official 01–Aug–2018)
- Glycine (RB posted 27–Jul–2018; official 01–Aug–2018)
- Metoprolol Succinate Extended-Release Tablets (RB posted 27–Jul–2018; official 01–Aug–2018)
- Rosuvastatin Tablets (RB posted 27–Jul–2018; official 01–Aug–2018)
- Tacrolimus Capsules (RB posted 27–Jul–2018; official 01–Aug–2018)
Official July 2018
- Benzonatate Capsules (RB posted 29–Jun–2018; official 01–Jul–2018)
- Fexofenadine Hydrochloride and Pseudoephedrine Extended-Release Tablets (RB posted 29–Jun–2018; official 01–Jul–2018; updated 27–Jul–2018; official 01–Aug–2018)
Official June 2018
- Moxidectin (RB posted 26–Jun–2018; official 27–Jun–2018)
- Diltiazem Hydrochloride Extended-Release Capsules (RB posted 11–Jun–2018; official 12–Jun–2018)
- Carbidopa and Levodopa Orally Disintegrating Tablets (RB posted 25–May–2018; official 01–Jun–2018)
- Nitrofurantoin Capsules (RB posted 25–May–2018; official 01–Jun–2018)
- Ondansetron Compounded Topical Gel (RB posted 25–May–2018; official 01–Jun–2018)
Official May 2018
- Amoxicillin Capsules (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Amoxicillin Tablets (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Aprepitant Capsules (RB posted 27–Apr–2018; official 01–May–2018) |En español
- Atorvastatin Calcium Tablets (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Bumetanide Tablets (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Doxycycline Capsules (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Epoetin (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Lamotrigine Extended-Release Tablets (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Levetiracetam Extended-Release Tablets (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Naproxen Sodium Tablets (IRA posted 29‒Sep‒2017; official 01‒May‒2018; updated 27–Oct–2017*) *The IRA for Naproxen Sodium Tablets was updated on October 27, 2017 to change the official date of the revision from November 1, 2017 to May 1, 2018. In addition, clarifications were made to the calculations statement and Sample stock solution under Organic Impurities section.
- Nevirapine Extended-Release Tablets (RB posted 27–Apr–2018; official 01–May–2018) | En español
- Ziprasidone Capsules (RB posted 27–Apr–2018; official 01–May–2018) | En Español
Official April 2018
- Doxycycline Tablets (RB posted 30–Mar–2018; official 01–Apr–2018)
- Oxybutynin Chloride Extended-Release Tablets (RB updated 26–Oct–2018, updated 02–Nov–2018; official 01–Apr–2018)
- Ritonavir Capsules (RB posted 30–Mar–2018; official 01–Apr–2018)
- Trazadone Hydrochloride Tablets (RB posted 30–Mar–2018; official 01–Apr–2018)
Official March 2018
- Esomeprazole Magnesium Delayed-Release Capsules (RB posted 23–Feb–2018; official 01–Mar–2018)
- Levetiracetam Tablets (RB posted 23–Feb–2018; official 01–Mar–2018)
- Salix Species Bark (posted 26–Jan–2018; official 01–Mar–2018) | En español
- Salix Species Bark Powder (posted 26–Jan–2018; official 01–Mar–2018) | En español
- Salix Species Bark Dry Extract (posted 26–Jan–2018; official 01–Mar–2018) | En español
Official February 2018
- Ezetimibe Tablets (RB posted 26–Jan–2018; official 01–Feb–2018) | En español
- Raloxifene Hydrochloride Tablets (RB posted 26–Jan–2018; official 01–Feb–2018) | En español
- Rivastigmine Tartrate Capsules (RB posted 29–Jan–2018; official 01–Feb–2018) | En español
- Telmisartan and Hydrochlorothiazide Tablets (RB posted 26–Jan–2018; official 01–Feb–2018) | En español