Revision Bulletins

Revision Bulletins are published in USP–NF Online by the first of each month. Each Revision Bulletin includes a notice that provides the reason for the change and the official date. Monograph names listed before April 1, 2021 contain a combined notice and documentary standard; postings after April 1, 2021 provide separate links for the notice and for the standard content. For more information on the Revision Bulletins and the Accelerated Revision process, see USP's Guideline on the Use of Accelerated Processes for Revisions to USP–NF and FCC. Archived Revision Bulletins can be found here.

See the Publication & Comment Schedule section for specific posting and official dates.

New and Updated Revision Bulletins

• Cyclophosphamide Capsules Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Fluorouracil Injection Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Guanfacine Extended-Release Tablets Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Metoprolol Succinate Extended-Release Tablets Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Somatropin  Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Somatropin for Injection Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Topiramate Extended-Release Capsules Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Bivalirudin Notice and Monograph (posted 30-May-2025; official 01-Jun-2025
• <382> Elastomeric Component Functional Suitability in Parenteral Product Packaging Systems Notice and Chapter (posted 25-Apr-2025; official 01-Dec-2025)
• Bisoprolol Fumarate Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Diltiazem Hydrochloride Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Fexofenadine Hydrochloride and Pseudoephedrine Hydrochloride Extended-Release Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Isotretinoin Capsules Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Tadalafil Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Carbamazepine Extended-Release Tablets Notice and Monograph (posted 10-Apr-2025; official 11-Apr-2025)
  • Previously published as a Pending Monograph Revision
• <123> Glucagon Identity Test Notice and Chapter (posted 28-Mar-2025; official 01-Apr-2025)
• Baclofen Tablets Notice and Monograph (posted 28-Mar-2025; official 01-Apr-2025)

Revision Bulletins

To view Accelerated Revisions by official date, please click here.

• <123> Glucagon Identity Test Notice and Chapter (posted 28-Mar-2025; official 01-Apr-2025)
• <382> Elastomeric Component Functional Suitability in Parenteral Product Packaging Systems Notice and Chapter (posted 25-Apr-2025; official 01-Dec-2025)
• <621> Chromatography Notice and Chapter (posted 31-Mar-2023; official 01-Apr-2023)
• <621> Chromatography Notice and Chapter (posted 28-Oct-2022; official 01-Dec-2023)
• <621> Chromatography Notice and Chapter (posted 29-Sep-2023; official 01-Oct-2023)
• <621> Notice and Chapter (posted 22-Nov-2024; official 01-Dec-2024)
• <661.1> Plastic Materials of Construction Notice and Chapter (posted 27-Jan-2023; official 01-Dec-2025)
• <661.1> Plastic Materials of Construction Notice and Chapter (posted 23-Feb-2024, official 01-Dec-2025)
• <665> Plastic Components and Systems Used to Manufacture Pharmaceutical Drug Products and Biopharmaceutical Drug Substances and Products Notice and Chapter (posted 29-Apr-2022; official 01-May-2026)
• <670> Auxiliary Packaging Components Notice and Chapter (posted 23-Feb-2024, official 01-Mar-2024)
• <825> Radiopharmaceuticals- Preparation, Compounding, Dispensing, and Repackaging Notice and Chapter (posted 29-Dec-2023; official 01-Jan-2024)
• Acetaminophen Extended-Release Tablets Notice and Monograph (posted 17-Nov-2023; official 01-Dec-2023)
• Acetazolamide Extended-Release Capsules Notice and Monograph (posted 17-Nov-2023; official 01-Dec-2023)
• Acetazolamide Extended-Release Capsules Notice and Monograph (posted 28-Jun-2024; official 01-Jul-2024)
• Acetazolamide Tablets Notice and Monograph (posted 26-Jan-2024; official 01-Feb-2024)
• Acyclovir Notice and Monograph (posted 29-Apr-2022; official 01-May-2023)
• Albuterol Inhalation Solution Notice and Monograph (posted 30–Apr–2021; official 01–Nov–2023) | En español
• Albuterol Inhalation Solution Notice and Monograph (posted 27-Oct-2023; official 01-May-2025)
• Albuterol Inhalation Solution Notice and Monograph (posted 31-Jan-2025; official 01-May-2026)
• Amantadine Hydrochloride Tablets Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
• Amitriptyline Hydrochloride Tablets Notice and Monograph (posted 25-May-2023; official 26-May-2023)
• Amphetamine Sulfate Tablets Notice and Monograph (posted 31-Jan-2025; official 01-Feb-2025)
• Ampicillin Capsules Notice and Monograph (posted 21-Dec-2023; official 22-Dec-2023)
• Anticoagulant Citrate Phosphate Dextrose Adenine Solution Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Anticoagulant Heparin Solution Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Antithrombin III Human Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Atorvastatin Calcium Tablets Notice and Monograph (posted 12-Jul-2023; official 13-Jul-2023)
• Atorvastatin Calcium Tablets Notice and Monograph (posted 25-Aug-2023; official 01-Sep-2023)
• Azithromycin for Oral Suspension Notice and Monograph (posted 26-Apr-2024, official 01-May-2024)
• Bacillus coagulans Notice and Monograph (posted 30-Jun-2023; official 01-Jul-2023)
• Baclofen Tablets Notice and Monograph (posted 28-Mar-2025; official 01-Apr-2025)
• Bisoprolol Fumarate Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Bivalirudin Notice and Monograph (posted 30-May-2025; official 01-Jun-2025
• Buprenorphine and Naloxone Sublingual Tablets Notice and Monograph (posted 25-Oct-2024; official 01-Nov-2024)
• Bupropion Hydrochloride Extended-Release Tablets Notice and Monograph (posted 28-Jul-2023; official 01- Aug-2023)
• Caffeine Citrate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Calcium Acetate Capsules Notice and Monograph (posted 25-Aug-2023; official 01-Sep-2023)
• Carbamazepine Extended-Release Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Carbamazepine Extended-Release Tablets Notice and Monograph (posted 29-Sep-2023; official 01-Oct-2023)
• Carbamazepine Extended-Release Tablets Notice and Monograph (posted 27-Oct-2023; official 01-Nov-2023)
• Carbamazepine Extended-Release Tablets Notice and Monograph (posted 31-Jan-2024; official 01-Feb-2024)
• Carbamazepine Extended-Release Tablets Notice and Monograph (posted 28-Jun-2024; official 01-Jul-2024)
• Carbamazepine Extended-Release Tablets Notice and Monograph (posted 10-Apr-2025; official 11-Apr-2025)
• Carbidopa and Levodopa Tablets Notice and Monograph (posted 29-Sep-2023; official 01-Oct-2023)
• Cetyl Palmitate Notice and Monograph (posted 28-Jun-2024; official 01-Jul-2024)
• Chlorpromazine Hydrochloride Tablets Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Chlorzoxazone Tablets Notice and Monograph (posted 30-Jun-2023; official 01-Jul-2023)
• Chlorthalidone Tablets Notice and Monograph (posted 27-Sep-2024; official 01-Oct-2024)
• Clarithromycin Extended-Release Tablets Notice and Monograph (posted 17-Nov-2023; official 01-Dec-2023)
• Clomipramine Hydrochloride Capsules Notice and Monograph (posted 28-Jun-2024; official 01-Jul-2024)
• Clonidine Hydrochloride Extended-Release Tablets Notice and Monograph (posted 30-Aug-2024; official 01-Sep-2024)
• Colchicine Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Cyclobenzaprine Hydrochloride Tablets Notice and Monograph (posted 29-Sep-2023; official 20-Sep-2023)
• Cyclophosphamide Capsules Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Dexamethasone Tablets Notice and Monograph (posted 11-Sep-2023; official 12-Sep-2023)
• Diclofenac Sodium Extended-Release Tablets Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Diclofenac Sodium and Misoprostol Delayed-Release Tablets Notice and Monograph (posted 12-Jul-2023; official 13-Jul-2023)
• Dicyclomine Hydrochloride Tablets Notice and Monograph (posted 25-Oct-2024; official 01-Nov-2024)
• Diltiazem Hydrochloride Extended-Release Capsules Notice and Monograph (posted 28-Apr-2023; official 01-May-2023)
• Diltiazem Hydrochloride Extended-Release Capsules Notice and Monograph (posted 29-Mar-2024, official 01-Apr-2024)
• Diltiazem Hydrochloride Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Doxepin Hydrochloride Capsules Notice and Monograph (posted 24-Feb-2023; official 01-Mar-2023)
• Dutasteride and Tamsulosin Hydrochloride Capsules Notice and Monograph (posted 26-Apr-2024, official 01-May-2024)
• Estradiol and Norethindrone Acetate Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Etoposide Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Famotidine Tablets Notice and Monograph (posted 28-Jul-2023; official 01-Aug-2023)
• Fexofenadine Hydrochloride Tablets Notice and Monograph (posted 26-Apr-2024, official 01-May-2024)
• Fexofenadine Hydrochloride and Pseudoephedrine Hydrochloride Extended-Release Tablets Notice and Monograph (posted 27-Oct-2023; official 01-Nov-2023)
• Fexofenadine Hydrochloride and Pseudoephedrine Hydrochloride Extended-Release Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Flecainide Acetate Tablets Notice and Monograph (posted 27-Oct-2023; official 01-Nov-2023)
• Fluorouracil Injection Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Fluoxetine Capsules Notice and Monograph (posted 24-Feb-2023; official 01-Mar-2023)
• Fluphenazine Decanoate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Fondaparinux Sodium Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Fosamprenavir Calcium Notice and Monograph (posted 27-Jan-2023; official 01-Feb-2023)
• Fosamprenavir Calcium Tablets Notice and Monograph (posted 25-Aug-2023; official 01-Sep-2023)
• Furosemide Injection Notice and Monograph (posted 31-Mar-2023; official 01-May-2023)
• Gamma Cyclodextrin Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Garcinia cambogia Notice and Monograph (psoted 22-Nov-2024; official 01-Dec-2024)
• Garcinia indica Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Guanfacine Tablets Notice and Monograph (posted 29-Nov-2023; official 30-Nov-2023)
• Guanfacine Tablets Notice and Monograph (posted 26-Jan-2024; official 01-Feb-2024)
• Guanfacine Extended-Release Tablets Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Hydroxychloroquine Sulfate Tablets Notice and Monograph (posted 17-Nov-2023; official 01-Dec-2023)
• Hydroxyurea Capsules Notice and Monograph (posted 26-Mar-2024, official 27-Mar-2024)
• Hydroxyzine Hydrochloride Tablets Notice and Monograph (posted 29-Mar-2024, official 01-Apr-2024)
• Iodixanol Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Iohexol Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Ioversol Injection Notice and Monograph (posted 27-Dec-2024; official 01-Jan-2025)
• Ipratropium Bromide Notice and Monograph (posted 28-Jul-2023; official 01-Aug-2023)
• Iron Dextran Injection Notice and Monograph (posted 04-Oct-2023; official 05-Oct-2023)
• Iron Sucrose Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Isosorbide Mononitrate Extended-Release Tablets Notice and Monograph (posted 26-Apr-2024, official 01-May-2024)
• Isotretinoin Capsules Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Ketamine Hydrochloride Notice and Monograph (posted 26-Jul-2024; official 01-Aug-2024)
• Ketoconazole Tablets Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Lamotrigine Extended-Release Tablets Notice and Monograph (posted 28-Jun-2024; official 01-Jul-2024)
• Levocarnitine Tablets Notice and Monograph (posted 26-Jul-2024; official 01-Aug-2024)
• Lithium Oral Solution Notice and Monograph (posted 18-Jun-2024; official 19-Jun-2024)
• Magnesium Sulfate Notice and Monograph (posted 25–Feb–2022; official 01–May–2023)
• Maltose Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
• Mesalamine Extended-Release Capsules Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
• Mesalamine Extended-Release Capsules Notice and Monograph (posted 17-Nov-2023; official 01-Dec-2023)
• Mesalamine Extended-Release Capsules Notice and Monograph (posted 28-Jun-2024; official 01-Jul-2024)
• Metformin Hydrochloride Extended-Release Tablets Notice and Monograph (posted 26-Jan-2024; official 01-Feb-2024)
• Methylene Blue Notice and Monograph (posted 31-Aug-2023; official 01-Sep-2023)
• Methyltestosterone  Capsules Notice and Monograph (posted 27-Dec-2024; official 01-Jan-2025)
• Metoprolol Succinate Extended-Release Tablets Notice and Monograph (posted 02-Nov-2022, official 03-Nov-2022)
• Metoprolol Succinate Extended-Release Tablets Notice and Monograph (posted 30-Aug-2024; official 01-Sep-2024)
• Metoprolol Succinate Extended-Release Tablets Notice and Monograph (posted 12-Sep-2024; official 13-Sep-2024)
• Metoprolol Succinate Extended-Release Tablets Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Midodrine Hydrochloride Tablets Notice and Monograph (posted 02-Nov-2023; official 01-Dec-2023)
• Minocycline Hydrochloride Extended-Release Tablets Notice and Monograph (posted 16-Feb-2023; official 17-Feb-2023)
• Minocycline Hydrochloride Extended-Release Tablets Notice and Monograph (posted 25-Aug-2023; official 01-Sep-2023)
• Minocycline Hydrochloride Extended-Release Tablets Notice and Monograph (posted 26-Apr-2024, official 01-May-2024)
• Mitotane Notice and Monograph (posted 28-Jul-2023; official 01-Aug-2023)
• Mitotane Notice and Monograph (posted 24-Jun-2022; official 01-Aug-2023)
• Mitotane Tablets Notice and Monograph (posted 28-Jul-2023; official 01-Aug-2023)
• Mitotane Tablets Notice and Monograph (posted 24-Jun-2022; official 01-Aug-2023)
• Naproxen Sodium and Pseudoephedrine Hydrochloride Extended-Release Tablets Notice and Monograph (posted 30-Aug-2024; official 01-Sep-2024)
• Nicardipine Hydrochloride Injection Notice and Monograph (posted 19-Sep-2023; official 20-Sep-2023)
• Nicardipine Hydrochloride Injection Notice and Monograph (posted 31-Jan-2025; official 01-Feb-2025)
• Nifedipine Extended-Release Tablets Notice and Monograph (posted 30-Aug-2024; official 01-Sep-2024)
• Nitrofurantoin Capsules Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
• Nitrofurantoin Capsules Notice and Monograph (posted 28-Apr-2023; official 01-Aug-2023)
• Olanzapine Tablets Notice and Monograph (posted 30-Jun-2023; official 01-Jul-2023)
• Olmesartan Medoxomil Tablets Notice and Monograph (posted 16-Aug-2023; official 17-Aug-2023)
• Olmesartan Medoxomil Tablets Notice and Monograph (posted 31-Jan-2025; official 01-Feb-2025)
• Pemetrexed Disodium Notice and Monograph (posted 06-Aug-2024; official 07-Aug-2024)
• Penicillamine Capsules Notice and Monograph (posted 28-Jul-2023; official 01-Aug-2023)
• Pirfenidone Tablets Notice and Monograph (posted 28-Mar-2025; official 01-Apr-2025)
• Potassium Citrate Extended-Release Tablets Notice and Monograph (posted 26-Jul-2024; official 01-Aug-2024)
• Powdered Garcinia cambogia Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Powdered Garcinia Hydroxycitrate Extract Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Powdered Garcinia indica Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Promethazine Hydrochloride Oral Solution Notice and Monograph (posted 27-Oct-2023; official 01-Nov-2023)
• Propranolol Hydrochloride Extended-Release Capsules Notice and Monograph (posted 29-Dec-2023; official 01-Jan-2024)
• Prazosin Hydrochloride Capsules Notice and Monograph (posted 08-May-2023; official 09-May-2023)
• Quetiapine Extended-Release Tablets Notice and Monograph (posted 29-Dec-2023; official 01-Jan-2024)
• Quetiapine Extended Release Tablets Notice and Monograph (posted 16-Aug-2023; official 17-Aug-2023)
• Quetiapine Extended-Release Tablets Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Ranitidine Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Rifabutin Capsules Notice and Monograph (posted 29-Dec-2023; official 01-Jan-2024)
• Risedronate Sodium Delayed-Release Capsules Notice and Monograph (posted 26-Apr-2024, official 01-May-2024)
• Roflumilast Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Sildenafil Tablets Notice and Monograph (posted 27-Dec-2024; official 01-Jan-2025)
• Sodium Thiosulfate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Somatropin  Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Somatropin for Injection Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Succinic Acid Notice and Monograph (posted 31-May-2024; official 01-Jun-2024)
• Sucrose Notice and Monograph (posted 26-May-2023; official 01-Jun-2023)
• Tadalafil Tablets Notice and Monograph (posted 25-Apr-2025; official 01-May-2025)
• Teriparatide Notice and Monograph (posted 11-Dec-2023; official 12-Dec-2023)
• Teriparatide Notice and Monograph (posted 29-Mar-2024, official 01-Apr-2024)
• Teriparatide Injection Notice and Monograph (posted 11-Dec-2023; official 12-Dec-2023)
• Topiramate Extended-Release Capsules Notice and Monograph (posted 22-Nov-2024; official 01-Dec-2024)
• Topiramate Extended-Release Capsules Notice and Monograph (posted 31-Jan-2025; official 01-Feb-2025)
• Topiramate Extended-Release Capsules Notice and Monograph (posted 27-Jun-2025; official 1-Jul-2025)
• Trehalose Notice and Monograph (posted 25-Oct-2024; official 01-Nov-2024)
• Trenbolone Acetate Notice and Monograph (posted 30-Jun-2023; official 01-Aug-2023)
• Trospium Chloride Tablets Notice and Monograph (posted 27-Dec-2024; official 01-Jan-2025)
• Tylosin Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Vigabatrin Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
• Vigabatrin Tablets Notice and Monograph (posted 28-Apr-2023; official 01-May-2023)