Revision Bulletins

Revision Bulletins are published in USP–NF Online by the first of each month. Each Revision Bulletin includes a notice that provides the reason for the change and the official date. Monograph names listed before April 1, 2021 contain a combined notice and documentary standard; postings after April 1, 2021 provide separate links for the notice and for the standard content. For more information on the Revision Bulletins and the Accelerated Revision process, see USP's Guideline on the Use of Accelerated Processes for Revisions to USP–NF. Archived Revision Bulletins can be found here.

See the Publication & Comment Schedule section for specific posting and official dates.

New and Updated Revision Bulletins

• Baclofen Injection Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Benztropine Mesylate Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Budesonide Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Potassium Citrate Extended-Release Tablets Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Chlorpromazine Hydrochloride Oral Concentrate Notice and Monograph (posted 14–Jun–2021; official 15–Jun–2021) Previously published as Pending- Notice of Intent to Revise

Revision Bulletins

To view Accelerated Revisions by official date, please click here.

• (+)-1-(9-Fluoroenyl) ethyl Chloroformate Solution Reagent and Notice (posted 28–May–2021; official 01–Jun–2021)
• <7> Labeling (posted 26–Apr–2019; official 01–May–2019) | En español
• <7> Labeling (posted 30–Aug–2019; official 01–Sep–2019) | En español
• <121> Insulin Assays (posted 29–Mar–2019; official 01–May–2019) | En español
• <661.1> Plastic Materials of Construction (posted 26–Feb–2021; official 01–Mar–2021)
• <795> Pharmaceutical Compounding— Nonsterile Preparations (posted 24–Apr–2020; official 01–May–2020)
• <797> Pharmaceutical Compounding— Sterile Preparations (posted 24–Apr–2020; official 01–May–2020)
• <800> Hazardous Drugs–Handling in Healthcare Settings (posted 26–Jun–2020; official 01–Jul–2020) | En español
• <825> Radiopharmaceuticals— Preparation, Compounding, Dispensing, and Repackaging (posted 29–May–2020; official 01–Dec–2020) | En español
• <1099> Limit on Number of Large Deviations When Assessing Content Uniformity in Large Samples- Postponement (posted 22–Feb–2019; official 01–Mar–2019) | En español
• Abiraterone Acetate Tablets (posted 18–Nov–2019; official 19–Nov–2019) | En español
• Abiraterone Acetate Tablets Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Albendazole Tablets (posted 02–Mar–2021; official 03–Mar–2021)
• Albuterol Inhalation Solution Notice and Monograph (posted 30–Apr–2021; official 01–Nov–2023)
• Alcohol (posted 17–Aug–2020; official 01–Sep–2020) | En español
• Alprazolam Tablets (posted 22–Feb–2019; official 01–Mar–2019) | En español
• Amiodarone Hydrochloride Tablets (posted 25–Oct–2019; official 01–Dec–2019) | En español
• Amiodarone Hydrochloride Tablets (posted 29–May–2020; official 01–Jun–2020)  | En español
• Amiodarone Hydrochloride Tablets (posted 29–Jan–2021; official 01–Feb–2021)
• Aminocaproic Acid Tablets (posted 10–Dec–2019; official 11–Dec–2019) | En español
• Amlodipine and Atorvastatin Tablets (posted posted 26–Nov–2019, official 27–Nov–2019) | En español
• Amlodipine and Olmesartan Medoxomil Tablets (posted 28–Feb–2020; official 01–Mar–2020) | En español
• Amlodipine and Olmesartan Medoxomil Tablets (posted 26–Mar–2021; official 01–Apr–2021)
• Atomoxetine Capsules (posted 31–Jan–2020; official 01–May–2020) | En español
• Atorvastatin Calcium Tablets (posted 22–Nov–2019; official 01–Dec–2019) | En español
• Atorvastatin Calcium Tablets (posted 25–Jan–2019; official 01–Feb–2019) | En español
• Baclofen Injection Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Benazepril Hydrochloride and Hydrochlorothiazide Tablets Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Bendamustine Hydrochloride (posted 22–Feb–2019; official 01–Mar–2019) | En español 
• Benzethonium Chloride (posted 25–Jan–2019; official 01–Feb–2019) | En español
• Benztropine Mesylate (posted 29–Jan–2021; official 01–May–2021)
• Benztropine Mesylate Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Budesonide Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Buprenorphine and Naloxone Sublingual Tablets (posted 31–Jul–2020; official 01–Aug–2020)  | En español 
• Bupropion Hydrochloride Notice and Monograph (posted 30–Apr–2021; official 01–Aug–2021)
• Bupropion Hydrochloride Extended-Release Tablets (posted 25–Jan–2019; official 01–Feb–2019) | En español
• Bupropion Hydrochloride Extended-Release Tablets (posted 18–Dec–2020; official 01–Jan–2021)
• Bupropion Hydrochloride Extended-Release Tablets (posted 26–Mar–2021; official 01–Aug–2021)
• Buspirone Hydrochloride Tablets Monograph and Notice (posted 28–May–2021; official 01–Jun–2021)
• Calcium Acetate Capsules (posted 26–Apr–2019; official 01–May–2019) | En español
• Calcium Acetate Capsules (posted 26–Dec–2019; official 01–Jan–2020) | En español
• Calcium Acetate Capsules (posted 20–Nov–2020; official 01–Dec–2020)
• Carbamazepine Extended-Release Tablets (posted 26–Dec–2019; official 01–May–2020) | En español
• Chlorpromazine Hydrochloride Tablets (posted 15–Sep–2020; official 16–Sep–2020)
• Chlorpromazine Hydrochloride Oral Concentrate Notice and Monograph (posted 14–Jun–2021; official 15–Jun–2021)
• Chlorzoxazone Tablets Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Cidofovir (posted 31–May–2019; official 01–Jun–2019) | En español
• Clomipramine Hydrochloride Capsules (posted 07–Jul–2020; official 08–Jul–2020) | En español
• Clonidine Hydrochloride Extended-Release Tablets Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Clonidine Transdermal System (posted 31–May–2019; official 01–Jun–2019) | En español
• Clonidine Transdermal System (posted 28–Aug–2020; official 01–Sep–2020) | En español
• Codeine Phosphate Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Cyclobenzaprine Hydrochloride (posted 26–Dec–2019; official 01–May–2020) | En español
• Cyclophosphamide for Injection (posted 25–Oct–2019; official 01–Nov–2019) | En español
• Dehydrated Alcohol (posted 17–Aug–2020; official 01–Sep–2020) | En español
• Dextrose Excipient (posted 28–Aug–2020; official 01–Sep–2020) | En español
• Diclofenac Sodium Topical Solution (posted 26–Mar–2021; official 01–Apr–2021)
• Diltiazem Hydrochloride Extended-Release Capsules (posted 26–Apr–2019; official 01–May–2019) | En español
• Diltiazem Hydrochloride Extended-Release Capsules (posted 31–Jan–2020; official 01–Feb–2020) | En español
• Diltiazem Hydrochloride Extended-Release Capsules (posted 26–Feb–2021; official 01– Mar–2021)
• Diphenydramine Hydrochloride and Ibuprofen Capsules (posted 24–Apr–2020; official 01–May–2020) 
• Divalproex Sodium Delayed-Release Capsules (posted 26–Mar–2021; official 01–Apr–2021)
• Divalproex Sodium Extended-Release Tablets (posted 18–Nov–2019; official 19–Nov–2019) | En español
• Donepezil Hydrochloride Tablets (posted 22–Feb–2019; official 01–Mar–2019) | En español
• Donepazil Hydrochloride Tablets (posted 24–Apr–2020; official 01–May–2020) | En español
• Dopamine Hydrochloride Injection (posted 28–Aug–2020; official 01–Sep–2020) | En español
• Doxepin Hydrochloride Capsules (posted 18–Dec–2020; official 01–May–2021)
• Doxepin Hydrochloride Capsules Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Doxycycline Calcium Oral Suspension (posted 26–Dec–2019; official 01–Jan–2020) | En español
• Doxycycline Hyclate Delayed-Release Tablets (posted 25–Sep–2020; official 01–Oct–2020)
• Doxycycline Hyclate Tablets (posted 28–Feb–2020; official 01–May–2020) | En español
• Drospirenone and Ethinyl Estradiol Tablets (posted 29–Mar–2019; official 01–Apr–2019) | En español
• Erythromycin Delayed-Release Tablets (posted 24–Jul–2019; official 25–Jul–2019) | En español
• Esomeprazole Magnesium Delayed-Release Capsules (posted 26–Jun–2020; official 01–Jul–2020)
• Estradiol Transdermal System (posted 22–Nov–2019; official 01–Dec–2019) | En español
• Ethacrynic Acid Tablets (posted 25–Sep–2020; official 01–Oct–2020)
• Ethacrynic Acid Tablets (posted 26–Mar–2021; official 01–Apr–2021)
• Extended Insulin Zinc Suspension (posted 29–Mar–2019; official 01–May–2019) | En español
• Fenofibrate Capsules (posted 26–Apr–2019; official 01–May–2019) | En español
• Fenofibrate Capsules Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Fexofenadine Hydrochloride Tablets (posted 18–Dec–2020; official 01–Jan–2021)
• Fluconazole Tablets (posted 31–Jan–2020; official 01–Feb–2020) |En español
• Fluphenazine Hydrochloride Tablets (posted 20–Jul–2020; official 21–Jul–2020) | En español
• Fluticasone Propionate and Salmeterol Inhalation Powder (posted 07–Feb–2019; official 08–Feb–2019) 
• Fondaparinux Sodium for Assay (posted 30–Oct–2020; official 01–Nov–2020)
• Glucagon for Injection (posted 25–Jan–2019; official 01–Feb–2019) | En español
• Indomethacin Suppositories (posted 22–Nov–2019; official 01–Dec–2019) | En español
• Insulin (posted 29–Mar–2019; official 01–May–2019) | En español
• Insulin Zinc Suspension (posted 29–Mar–2019; official 01–May–2019) | En español
• Iohexol (posted 26–Jul–2019; official 01–Aug–2019) | En español
• Isophane Insulin Suspension (posted 29–Mar–2019; official 01–May–2019) | En español
• Isosorbide Mononitrate Extended-Release Tablets (posted 27–Sep–2019; official 01–Oct–2019) | En español
• Itraconazcole Capsules (posted 31–May–2019; official 01–Aug–2019) | En español
• Lactobacillus rhamnosus (posted 18–Dec–2020; official 01–May–2021)
• Lamotrigine Extended-Release Tablets (posted 25–Jan–2019; official 01–Feb–2019) | En español
• Lauroyl Polyoxyglycerides Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Levetiracetam Extended-Release Tablets (posted 26–Dec–2019; official 01–Jan–2020) | En español
• Levetiracetam Oral Solution (posted 22–Nov–2019; official 01–Dec–2019) | En español
• Levothyroxine Sodium Tablets (posted 27–Sep–2019; official 01–Oct–2019) | En español
• Loperamide Hydrochloride (posted 29–May–2020; official 01–Nov–2020) | En español
• Lovastatin Tablets Monograph and Notice (posted 28–May–2021; official 01–Jun–2021)
• Manganese Sulfate Injection (posted 26–Jul–2019; official 01–Aug–2019) | En español
• Mesalamine Delayed-Release Tablets (posted 22–Nov–2019; 01–May–2020) | En español
• Mesalamine Delayed-Release Tablets (posted 24–Apr–2020; updated 01–May–2020; official 01–Nov–2020) | En español
• Mesalamine Delayed-Release Tablets (posted 31–Jul–2020; official 01–Nov–2020) | En español
• Mesalamine Delayed-Release Tablets Monograph and Notice (posted 28–May–2021; official 01–Jun–2021)
• Mesalamine Extended-Release Capsules (posted 29–May–2020; official 01–Jun–2020) | En español
• Metaxolone Tablets (posted 28–Aug–2020; official 01–Sep–2020) | En español
• Metformin Hydrochloride Extended-Release Tablets (posted 22–Feb–2019; official 01–Mar–2019) | En español
• Metformin Hydrochloride Extended-Release Tablets (posted 27–Apr–2020; official 28–Apr–2020) | En español
• Metformin Hydrochloride Extended-Release Tablets (posted 18–Dec–2020; official 01–Jan–2021)
• Metoprolol Succinate Extended-Release Tablets (posted 30–Oct–2020; official 01–Nov–2020)
• Methotrexate Injection (posted 26–Apr–2019; official 01–May–2019) | En español
• Methylphenidate Hydrochloride Extended-Release Tablets (posted 26–Jul–2019; official 01–Aug–2019) | En español
• Methylphenidate Hydrochloride Extended-Release Tablets (posted 22–Nov–2019; official 01–Dec–2019) | En español
• Methylphenidate Hydrochloride Extended-Release Tablets (posted 25–Sep–2020; official 01–Oct–2020)
• Methylphenidate Hydrochloride Extended-Release Tablets (posted 18–Dec–2020; official 01–Jan–2021)
• Metyrosine Capsules (posted 21–Sep–2020; official 22–Sep–2020)
• Miconazole Nitrate (posted 26–Apr–2019; official 01–May–2019) | En español
• Minocycline Hydrochloride Extended-Release Tablets (posted 30–Aug–2019; official 01–Sep–2019) | En español
• Minocycline Hydrochloride Extended-Release Tablets (posted 18–Dec–2020; official 01–Jan–2021)
• Montelukast Sodium Chewable Tablets (posted 29–May–2020; official 01–Jun–2020) | En español
• Montelukast Sodium Tablets (posted 22–Nov–2019; official 01–May–2020) | En español
• N-Acetylglucosamine (posted 29–May–2020; official 01–Jun–2020) | En español
• Naloxone Hydrochloride Injection (posted 28–Aug–2020; official 01–Sep–2020) | En español
• Naproxen Sodium and Pseudoephedrine Hydrochloride Extended-Release Tablets (posted 22–Feb–2019; official 01–Mar–2019) | En español
• Niacin Extended-Release Tablets (posted 31–Jul–2020; official 01–Aug–2020) | En español
• Nicotine Transdermal System (posted 18–Dec–2020; official 01–Jan–2021)
• Nifedipine Extended-Release Tablets (posted 22–Nov–2019; official 01–May–2020) | En español
• Nifedipine Extended-Release Tablets (posted 26–Mar–2021; official 01–Apr–2021)
• Nitrofurantoin Capsules (posted 30–Oct–2020; official 01–Nov–2020)
• Nitrofurantoin Capsules Monograph and Notice (posted 28–May–2021; official 01–Jun–2021)
• Olanzapine Tablets (posted 24–Apr–2020; official 01–May–2020) | En español
• Olmesartan Medoxomil Tablets (posted 18–Mar–2019; official 19–Mar–2019)
• Olmesartan Medoxomil Tablets (posted 30–Aug–2019; official 01–Sep–2019)
• Olmesartan Medoxomil Tablets (posted 31–Jan–2020; official 01–Feb–2020) | En español
• Oxybutynin Chloride Extended-Release Tablets (posted 27–Sep–2019; official 01–Oct–2019) | En español
• Oxybutynin Chloride Tablets (posted 26–Mar–2021; official 01–Apr–2021) 
• Pantoprazole Sodium Delayed-Release Tablets (posted 26–Apr–2019; official 01–May–2019) | En español
• Parachlorophenol (posted 30–Oct–2020; official 01–Nov–2020)
• Penicillamine Capsules (posted 10–Jun–2019; official 11–Jun–2019) | En español
• Polyethylene Glycol 3350 (posted 20–Nov–2020, updated 25–Nov–2020; official 01–Dec–2020)
• Potassium Chloride Extended-Release Capsules (posted 18–Dec–2020; official 01–Jan–2021)
• Potassium Chloride Extended-Release Tablets (posted 31–Jul–2019; official 01–Aug–2019) | 
• Potassium Chloride Extended-Release Tablets (posted 20–Aug–2019; official 21–Aug–2019)
• Potassium Chloride Extended-Release Tablets (posted 30–Aug–2019; official 01–Sep–2019) | En español
• Potassium Chloride Extended-Release Tablets (posted 23–Mar–2020; official 24–Mar–2020) | En español
• Potassium Chloride Extended-Release Tablets (posted 18–May–2020; official 19–May–2020) | En español
• Potassium Citrate Extended-Release Tablets (posted 30–Oct–2020; official 01–Nov–2020)
• Potassium Citrate Extended-Release Tablets Notice and Monograph (posted 25–Jun–2021; official 01–Jul–2021)
• Prasugrel Tablets Monograph and Notice (posted 28–May–2021; official 01–Aug–2021)
• Prazosin Hydrochloride Capsules (posted 26–Jun–2020; official 01–Jul–2020) | En español
  Propafenone Hydrochloride Extended-Release Capsules (posted 06–Aug–2020; official 07–Aug–2020) | En español
• Prednisone Tablets (posted 07–Jul–2020; official 08–Jul–2020) | En español
• Prompt Insulin Zinc Suspension (posted 29–Mar–2019; official 01–May–2019) | En español
• Propafenone Hydrochloride Extended-Release Capsules (posted 07–Mar–2019; official 08–Mar–2019) | En español
• Propranolol Hydrochloride Extended-Release Capsules (posted 31–Jul–2020; official 01–Aug–2020) | En español
• Psuedoephedrine Hydrochloride Extended-Release Tablets (posted 22–Feb–2019; official 01–Mar–2019) | En español
• Pyrazinamide Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Quetiapine Extended-Release Tablets (posted 29–Mar–2019; official 01–Apr–2019) | En español
• Quetiapine Extended-Release Tablets (posted 28–Dec–2018; official 01–Jan–2019) | En español
• Quinine Sulfate Capsules (posted 31–Jul–2020; official 01–Aug–2020) | En español
• Ropinirole Extended-Release Tablets (posted 28–Jun–2019; official 01–Jul–2019) | En español
• Ropivacaine Hydrochloride (posted 23–Feb–2021; official 24–Feb–2021)
• Rosuvastatin Tablets (posted 29–Mar–2019; official 01–Apr–2019) | En español
• Rufinamide Tablets Notice and Monograph (posted 30–Apr–2021; official 01–May–2021)
• Tadalafil Tablets (posted 25–Oct–2019; official 01–Nov–2019) | En español
• Taurine (posted 22–Feb–2019; official 01–Mar–2019) | En español 
• Telmisartan and Amlodipine Tablets (posted 25–Jan–2019; official 01–Feb–2019) | En español
• Tranexamic Acid Tablets (posted 26–Jul–2019; official 01–Aug–2019) | En español
• Triamcinolone Acetonide Nasal Spray (posted 25–Jan–2019; official 01–May–2019) | En español
• Vancomycin Injection (posted 28–Feb–2019; official 01–Mar–2019) | En español
• Ziprasidone Capsules (posted 27–Sep–2019; official 01–Oct–2019) | En español
• Zolmitriptan Orally Disintegrating Tablets (posted 24–Apr–2020; official 01–May–2020) | En español