Revision Bulletins

Revision Bulletins are published in USP–NF Online by the first of each month. Each Revision Bulletin includes a notice that provides the reason for the change and the official date. Monograph names listed before April 1, 2021 contain a combined notice and documentary standard; postings after April 1, 2021 provide separate links for the notice and for the standard content. For more information on the Revision Bulletins and the Accelerated Revision process, see USP's Guideline on the Use of Accelerated Processes for Revisions to USP–NF and FCC. Archived Revision Bulletins can be found here.

See the Publication & Comment Schedule section for specific posting and official dates.

New and Updated Revision Bulletins

  • Isosorbide Dinitrate Tablets Notice and Monograph (posted 26-May-2023; official 01-Jun-2023)
  • Sodium Bicarbonate Notice and Monograph (posted 26-May-2023; official 01-Jun-2023)
  • Sorafenib Tablets Notice and Monograph (posted 26-May-2023; official 01-Jun-2023)
  • Sucrose Notice and Monograph (posted 26-May-2023; official 01-Jun-2023)
  • Amitriptyline Hydrochloride Tablets Notice and Monograph (posted 25-May-2023; official 26-May-2023)
    • Previously published as a Pending Revision Notice
  • Prazosin Hydrochloride Capsules Notice and Monograph (posted 08-May-2023; official 09-May-2023)
    • Previously published as a Pending Revision Notice
  • Diltiazem Hydrochloride Extended-Release Capsules Notice and Monograph (posted 28-Apr-2023; official 01-May-2023)
  • Nitrofurantoin Capsules Notice and Monograph (posted 28-Apr-2023; official 01-Aug-2023)
  • Vigabatrin Tablets Notice and Monograph (posted 28-Apr-2023; official 01-May-2023)
  • <621> Chromatography Notice and Chapter (posted 31-Mar-2023; official 01-Apr-2023)
  • Anticoagulant Citrate Phosphate Dextrose Adenine Solution Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Anticoagulant Heparin Solution Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Antithrombin III Human Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Caffeine Citrate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Carbamazepine Extended-Release Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Colchicine Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Estradiol and Norethindrone Acetate Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Etoposide Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Fluphenazine Decanoate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Fondaparinux Sodium Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Furosemide Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Iodixanol Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Iohexol Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Iron Sucrose Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Ranitidine Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Sodium Thiosulfate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Tylosin Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Vigabatrin Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Doxepin Hydrochloride Capsules Notice and Monograph (posted 24-Feb-2023; official 01-Mar-2023)
  • Fluoxetine Capsules Notice and Monograph (posted 24-Feb-2023; official 01-Mar-2023)
  • Minocycline Hydrochloride Extended-Release Tablets Notice and Monograph (posted 16-Feb-2023; official 17-Feb-2023)
    • Previously posted as a Pending Revision Notice

Revision Bulletins

To view Accelerated Revisions by official date, please click here.

  • <621> Chromatography Notice and Chapter (posted 31-Mar-2023; official 01-Apr-2023)
  • <621> Chromatography Notice and Chapter (posted 28-Oct-2022; official 01-Dec-2023)
  • <661.1> Plastic Materials of Construction Notice and Chapter (posted 27-Jan-2023; official 01-Dec-2025)
  • <665> Plastic Components and Systems Used to Manufacture Pharmaceutical Drug Products and Biopharmaceutical Drug Substances and Products Notice and Chapter (posted 29-Apr-2022; official 01-May-2026)
  • Acetaminophen Extended-Release Tablets Notice and Monograph (posted 30-Sep-2022; official 01-Oct-2022)
  • Acyclovir Notice and Monograph (posted 29-Apr-2022; official 01-May-2023)
  • Albuterol Inhalation Solution Notice and Monograph (posted 30–Apr–2021; official 01–Nov–2023) | En español
  • Amantadine Hydrochloride Tablets Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
  • Amitriptyline Hydrochloride Tablets Notice and Monograph (posted 25-May-2023; official 26-May-2023)
  • Anticoagulant Citrate Phosphate Dextrose Adenine Solution Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Anticoagulant Heparin Solution Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Antithrombin III Human Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Azithromycin for Oral Suspension Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Caffeine Citrate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Calcipotriene Ointment Notice and Monograph (posted 29-Apr-2022; official 01-Aug-2022)
  • Carbamazepine Extended-Release Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Carbamazepine Tablets Notice and Monograph (posted 21-Sep-2022; official 22-Sep-2022)
  • Carbidopa and Levodopa Tablets Notice and Monograph (posted 28-Oct-2022; official 01-Nov-2022)
  • Colchicine Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Desipramine Hydrochloride Tablets Notice and Monograph (posted 31–Dec–2021; official 01–Jan–2022)
  • Dextran 40 Notice and Monograph (posted 25–Mar–2022; official 01–Jul–2022)
  • Dextran 70 Notice and Monograph (posted 25–Mar–2022; official 01–Jul–2022)
  • Dextrose Injection Notice and Monograph (posted 19–Nov–2021; official 01–Jun–2022)
  • Dextrose Injection Notice and Monograph (posted 29-Apr-2022; official 01-Jun-2022)
  • Diatrizoate Meglumine and Diatrizoate Sodium Solution Notice and Monograph (posted 19-Jul-2022; official 20-Jul-2022)
  • Diethylene Glycol Stearates Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Digoxin Tablets Notice and Monograph (posted 24-Jun-2022; official 01-Jul-2022)
  • Diltiazem Hydrochloride Extended-Release Capsules Notice and Monograph (posted 28-Apr-2023; official 01-May-2023)
  • Doxepin Hydrochloride Capsules Notice and Monograph (posted 24-Feb-2023; official 01-Mar-2023)
  • Doxycycline Hyclate Tablets Notice and Monograph (posted 08-Nov-2022; official 09-Nov-2022)
  • Esomeprazole Magnesium Notice and Monograph (posted 19-Dec-2022; official 20-Dec-2022)
  • Estradiol and Norethindrone Acetate Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Etoposide Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Fluoxetine Capsules Notice and Monograph (posted 24-Feb-2023; official 01-Mar-2023)
  • Fluphenazine Decanoate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Fondaparinux Sodium Notice and Monograph (posted 29-Apr-2022; official 01-Aug-2022)
  • Fondaparinux Sodium Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Fosamprenavir Calcium Notice and Monograph (posted 27-Jan-2023; official 01-Feb-2023)
  • Furosemide Injection Notice and Monograph (posted 31-Mar-2023; official 01-May-2023)
  • Guanfacine Extended-Release Tablets Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Guanfacine Extended-Release Tablets Notice and Monograph (posted 28-Oct-2022; official 01-Nov-2022)
  • Hydroxychloroquine Sulfate Tablets Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Iodixanol Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Iohexol Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Iron Sucrose Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Lacosamide Tablets Notice and Monograph (posted 30-Sep-2022; official 01-Oct-2022)
  • Lamotrigine Extended Release Tablets Notice and Monograph (posted 28-Oct-2022; official 01-Nov-2022)
  • Levetiracetam Tablets Notice and Monograph (posted 15-Jun-2022; official 16-Jun-2022)
  • Levothyroxine Sodium Tablets Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Loratadine Capsules Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Magnesia Tablets Notice and Monograph (posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Carbonate Notice and Monograph (posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Hydroxide Notice and Monograph (posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Hydroxide Paste Notice and Monograph (posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Oxide Notice and Monograph (posted 19–Nov–2021; official 01–Dec–2022)
  • Magnesium Sulfate Notice and Monograph (posted 25–Feb–2022; official 01–May–2023)
  • Magnesium Trisilicate Notice and Monograph (posted 19–Nov–2021; official 01–Dec–2022)
  • Maltose Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
  • Mesalamine Extended-Release Capsules Notice and Monograph (posted 30-Sep-2022; official 01-Oct-2022)
  • Mesalamine Extended-Release Capsules Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
  • Metoprolol Succinate  Extended-Release Tablets Notice and Monograph (posted 02-Nov-2022; official 03-Nov-2022)
  • Methylprednisolone Tablets Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Mexiletine Hydrochloride Capsules Notice and Monograph (posted 24-Jun-2022; official 01-Jul-2022)
  • Milk of Magnesia Notice and Monograph (posted 19–Nov–2021; official 01–Dec–2022) 
  • Minocycline Hydrochloride Extended-Release Tablets Notice and Monograph (posted 16-Feb-2023; official 17-Feb-2023)
  • Mitotane Notice and Monograph (posted 24-Jun-2022; official 01-Aug-2023)
  • Mitotane Tablets Notice and Monograph (posted 24-Jun-2022; official 01-Aug-2023)
  • Nitrofurantoin Capsules Notice and Monograph (posted 16-Dec-2022; official 01-Jan-2023)
  • Nitrofurantoin Capsules Notice and Monograph (posted 28-Apr-2023; official 01-Aug-2023)
  • Nortriptyline Hydrochloride Capsules Notice and Monograph (posted 30-Sep-2022; official 01-Oct-2022)
  • Potassium Citrate Extended-Release Tablets Notice and Monograph (posted 27–May–2022; official 01–Jun–2022)
  • Prazosin Hydrochloride Capsules Notice and Monograph (posted 08-May-2023; official 09-May-2023)
  • Prochlorperazine Maleate Tablets Notice and Monograph (posted 06-Sep-2022; official 07-Sep-2022)
  • Ranitidine Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Rifabutin Notice and Monograph (posted 30-Sep-2022; official 01-Oct-2022)
  • Rufinamide Tablets Notice and Monograph (posted 15-Sep-2022; official 16-Sep-2022)
  • Sodium Thiosulfate Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Tacrolimus Capsules Notice and Monograph (posted 02-Nov-2022; official 03-Nov-2022)
  • Temozolomide Capsules Notice and Monograph (posted 26-Aug-2022; official 01-Sep-2022)
  • Terazosin Capsules Notice and Monograph (posted 24-Jun-2022; official 01-Jul-2022)
  • Tobramycin Sulfate Notice and Monograph (posted 08-Nov-2022; official 09-Nov-2022)
  • Tylosin Injection Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Venlafaxine Hydrochloride Extended-Release Capsules Notice and Monograph (posted 26-Aug-2022; official 01-Sep-2022)
  • Vigabatrin Tablets Notice and Monograph (posted 31-Mar-2023; official 01-Apr-2023)
  • Vigabatrin Tablets Notice and Monograph (posted 28-Apr-2023; official 01-May-2023)