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Type of Posting: Notice of Intent to Revise
Posting Date: 26–Jun–2020
Targeted Official Date: 01–Mar–2021, Interim Revision Announcement
Expert Committee: Non-Botanical Dietary Supplements

In accordance with section 9.04 (c) of the 2020–2025 Rules and Procedures of the Council of Experts, this is to provide notice that the Non-Botanical Dietary Supplements Expert Committee intends to revise the Ribose monograph.

USP has received comments to the Ribose monograph, as published in the Second Supplement to USP 43–NF 38 with supporting data indicating that the conditions for the Loss on Drying test procedure should be revised. The Expert Committee proposes to revise this procedure as follows:

  • The Analysis conditions for the test for Loss on Drying will be changed from “Dry at 105° for 2 h” to “Dry at 60° under vacuum of NLT 50 mmHg for 3.5 h.”

It is anticipated that the proposed revision will be published as an Interim Revision Announcement (IRA) in Pharmacopeial Forum 46(5) [Sep.–Oct. 2020] pursuant to the Rules and Procedures. The comment period for this revision ends on November 30, 2020. In the absence of any adverse comments, the proposed IRA will become official on March 1, 2021. 

Should you have any questions, please contact Fatkhulla Tadjimukhamedov, Scientific Liaison to the Non-Botanical Dietary Supplements Expert Committee (301–230–3216 or