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High Fructose Corn Syrup

Type of Posting: Notice of Intent to Revise

Posting Date: 26–Oct–2012

Targeted Official Date: Interim Revision Announcement, 01–Jul–2013

Expert Committee: Monographs—Excipients

In accordance with section 7.05(c) of the 2010–2015 Rules and Procedures of the Council of Experts, this is to provide notice that the USP Monographs—Excipients Committee intends to revise the High Fructose Corn Syrup monograph to update the monograph’s Definition for percentage of fructose, to represent articles in commerce. The IRA is also revising the Assay procedure, specifically on the calculations.

It is anticipated that the proposed revision will be published as an Interim Revision Announcement (IRA) in Pharmacopeial Forum 39(1) [Jan–Feb 2013], pursuant to section 7.02 of the Rules and Procedures.

Should you have questions, please contact Hong Wang, Senior Scientific Liaison to the Expert Committee (301-816-8351 or