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PDF CSV October 31, 2022 through October 31, 2024 See all Errata for USP–NF How to use
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Monograph Title Section Source Publication Page Number Errata Official Date Target Errata Print Publication Target Online Fix Publication Description
FLUTICASONE PROPIONATE NASAL SPRAY OTHER COMPONENTS/Content of Phenylethyl Alcohol USPNF Online Online 1-May-2023 NA NA In Sample solution: Change
Transfer 1.0 g of the Nasal Spray to a 50-mL volumetric flask. Add about 40 mL of Diluent, and sonicate for 10 min until the supernatant is clear. Use the clear supernatant for analysis.
to:
Transfer 1.0 g of the… Read More
PSEUDOEPHEDRINE HYDROCHLORIDE TABLETS PERFORMANCE TESTS USPNF Online Online 1-May-2023 NA NA Change
Uniformity of Dosage Units 〈905〉
Procedure for content uniformity

to:
Uniformity of Dosage Units 〈905〉: Meets the requirements
Procedure for content uniformity, chewable tablets only

AND
In Read More
ACARBOSE TABLETS IDENTIFICATION/B. USPNF Online Online 1-May-2023 NA NA Change
The spectrum obtained from the Sample solution shows IR maxima in the regions of 3500–3200, 2950–2890, 1653–1633, and 1070–1000 cm–1.
to:
The spectrum obtained from the sample preparation shows IR maxima in the regions of 3500–3200… Read More
POLYETHYLENE GLYCOL 12 CETOSTEARYL ETHER IDENTIFICATION USPNF Online Online 1-Aug-2023 NA NA Change:
B. Test for Hydroxyl Group:
to:
B. Hydroxyl Value:
AND
In D./Analysis: Change
Dissolve or disperse the Sample in alcohol.
to:
Dissolve or disperse the Read More
VIGABATRIN TABLETS IMPURITIES/Organic Impurities USPNF Online Online 1-May-2023 NA NA In Analysis: Change
CS = concentration of USP Vigabatrin Related Compound A in the Standard solution
to:
CS = concentration of USP Vigabatrin Related Compound A RS in the Standard solution
ROSEMARY LEAF DRY AQUEOUS EXTRACT COMPOSITION/Content of Rosmarinic Acid USPNF Online Online 1-May-2023 NA NA In Standard solution B: Change
Before injection, pass through a membrane filter of 0.45-µL or finer pore size,
to:
Before injection, pass through a membrane filter of 0.45-µm or finer pore size,
AND
In Sample solution: Change
Read More
BUPIVACAINE HYDROCHLORIDE INJECTION ASSAY/Procedure USPNF Online Online 1-May-2023 NA NA In Chromatographic system/Column: Change
4-mm × 30-cm; packing L1
to:
3.9-mm × 30-cm; packing L1
AND
In System suitability: Change
[Note—The relative retention times for bupivacaine hydrochloride and dibutyl phthalate are… Read More
ESCITALOPRAM TABLETS ASSAY/Procedure USPNF Online Online 1-May-2023 NA NA In Buffer: Change
Adjust with 1 N sodium hydroxide VS to a pH of 5.2.
to:
Adjust with 1 N sodium hydroxide to a pH of 5.2.
<1042> CELL BANKING PRACTICES FOR RECOMBINANT BIOLOGICS 5. CELL BANK CHARACTERIZATION USPNF Online Online 1-May-2023 NA NA In Table 4: Change
In vitro assayd,e + + +f
to:
In vitro assayd,e + −f +
CALCIUM LACTATE CHEMICAL INFORMATION USPNF Online Online 1-Apr-2023 NA NA Change
Calcium lactate (1:2) hydrate
to:
Calcium lactate hydrate
AND
Change
Calcium lactate (1:2) pentahydrate
to:
Calcium lactate pentahydrate
THYROID ASSAY/Procedure USPNF Online Online 1-Apr-2023 NA NA In Chromatographic system: Change
Column: 4.6-cm × 25-cm; packing L1
to:
Column: 4.6-mm × 25-cm; packing L1
PRAZOSIN HYDROCHLORIDE CAPSULES ASSAY/Procedure USPNF Online Online 1-Apr-2023 NA NA In Analysis: Change
CS = concentration of USP Prazosin Hydrochloride RS in the Standard solution (µg/mL)
CU = nominal concentration of prazosin in the Sample solution (µg/mL)
Mr1… Read More
ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE TABLETS IMPURITIES/Limit of 2-Methylbenzhydrol USPNF Online Online 1-Apr-2023 NA NA In Standard solution: Change
7.5 µg/mL of USP 2-Methylbenzhydrol RS in methanol
to:
7.5 µg/mL of USP Methylbenzhydrol RS in methanol
AND
In Analysis: Change
CS = concentration of USP 2-Methylbenzhydrol RS in the… Read More
ERYTHROMYCIN ETHYLSUCCINATE FOR ORAL SUSPENSION Identification USPNF Online Online 1-Apr-2023 NA NA Change
Proceed as directed in the Identification test under Erythromycin Ethylsuccinate Oral Suspension, beginning with “Prepare a Standard solution.”
to:
Prepare a Standard solution of USP Erythromycin Ethylsuccinate RS in methanol… Read More
<209> LOW MOLECULAR WEIGHT HEPARIN MOLECULAR WEIGHT DETERMINATIONS PROCEDURE USPNF Online Online 1-Apr-2023 NA NA In footnote 1 in Molecular Weight Measurements of Low Molecular Weight Heparins by Gel Permeation Chromatography/Chromatographic system/Columns/Analytical: Change
guard column TSK SWXL 6-mm × 4-mm;
to:
guard column TSK… Read More
LEVORPHANOL TARTRATE TABLETS PERFORMANCE TESTS/Uniformity of Dosage Units 〈905〉 USPNF Online Online 1-Aug-2023 NA NA In Sample solution: Change
Nominally about 80 ug/mL of levorphanol tartrate in Diluent prepared as follows.
to:
Nominally about 80 µg/mL of levorphanol tartrate in Diluent prepared as follows.
THYROID TABLETS ASSAY/Procedure USPNF Online Online 1-Apr-2023 NA NA In Chromatographic system: Change
Column: 4.6-cm × 25-cm; packing L1
to:
Column: 4.6-mm × 25-cm; packing L1
PRAZOSIN HYDROCHLORIDE CAPSULES PERFORMANCE TESTS/Dissolution 〈711〉 USPNF Online Online 1-Apr-2023 NA NA In Test 2/Analysis: Change
CS = concentration of USP Prazosin Hydrochloride RS in the Standard solution (µg/mL)
to:
CS = concentration of USP Prazosin Hydrochloride RS in the Standard… Read More
ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE TABLETS ADDITIONAL REQUIREMENTS/USP Reference Standards 〈11〉 USPNF Online Online 1-Apr-2023 NA NA Change
USP 2-Methylbenzhydrol RS
to:
USP Methylbenzhydrol RS
ERYTHROMYCIN ETHYLSUCCINATE FOR ORAL SUSPENSION Assay USPNF Online Online 1-Apr-2023 NA NA Change
Constitute Erythromycin Ethylsuccinate for Oral Suspension as directed in the labeling, and proceed as directed in the Assay under Erythromycin Ethylsuccinate Oral Suspension.
to:
Constitute Erythromycin Ethylsuccinate for Oral… Read More
DEXTRATES ASSAY/Dextrose Equivalent USPNF Online Online 1-May-2023 NA NA In Analysis: Change
rA = peak response of each saccharide degree of polymerization (DP1–DP3) in the Sample solution (If any peaks of DP4 and above are observed in the sample, take the summation… Read More
NORETHINDRONE ACETATE AND ETHINYL ESTRADIOL TABLETS PERFORMANCE TESTS/Dissolution 〈711〉 USPNF Online Online 1-Apr-2023 NA NA In Test 2/Analysis: Change
CS = concentration of USP Norethindrone Acetate RS (mg/mL) or USP Ethinyl Estradiol RS (ug/mL) in the Standard solution
to:
CS = concentration of USP Norethindrone Acetate… Read More
ERYTHROMYCIN DELAYED-RELEASE TABLETS PERFORMANCE TESTS/Dissolution 〈711〉 USPNF Online Online 1-Apr-2023 NA NA In Test 1: Change
Buffer stage
Medium: 0.05 M pH 6.8 phosphate buffer (see Reagents, Indicators, and Solutions—Buffer Solutions)
to:
Buffer stage
Medium: 0.05 M pH 6.8 phosphate buffer (see Reagents,… Read More
SOTALOL HYDROCHLORIDE IMPURITIES/Organic Impurities USPNF Online Online 1-Mar-2023 NA NA In Analysis: Change
Calculate the percentage of any unspecified impurities in the portion of Sotalol Hydrochloride taken:
Result = (rU/rS) × (CS/CU) × 100
r… Read More
LIDOCAINE HYDROCHLORIDE AND DEXTROSE INJECTION Assay for lidocaine hydrochloride USPNF Online Online 1-Mar-2023 NA NA Change
Proceed with Injection as directed in the Assay for lidocaine hydrochloride under Lidocaine and Epinephrine Injection.
to:
Proceed with Injection as directed in the Assay for lidocaine hydrochloride under Lidocaine… Read More
TRIETHYL CITRATE ASSAY/Procedure USPNF Online Online 1-May-2023 NA NA In System suitability/Suitability requirements/Tailing factor: Change
NMT 1.5 for the triethyl citrate to trimethyl citrate peaks
to:
NMT 1.5 for the triethyl citrate and trimethyl citrate peaks
METAPROTERENOL SULFATE TABLETS Identification/A. USPNF Online Online 1-Mar-2023 NA NA Change
Proceed as directed in Identification test A under Metaproterenol Sulfate Inhalation Solution, beginning with “Allow the spots to dry”:
to:
Allow the spots to dry, and develop the chromatogram in a solvent system consisting… Read More
GLYCYL-L-TYROSINE IMPURITIES/Related Compounds USPNF Online Online 1-Jun-2023 NA NA In Buffer solution: Change
Dissolve 6.84 g of potassium phosphate in 1000 mL of water.
to:
Dissolve 6.84 g of monobasic potassium phosphate in 1000 mL of water.
MIRTAZAPINE TABLETS IMPURITIES/Organic Impurities USPNF Online Online 1-Mar-2023 NA NA In System suitability/Suitability requirements/Resolution: Change
10-ketomirtazpine
to:
10-ketomirtazapine
AND
In Table 1: Change
1-Ketomirtazpinec
to:
1-Ketomirtazapinec
METAPROTERENOL SULFATE ORAL SOLUTION Identification/A. USPNF Online Online 1-Mar-2023 NA NA Change
Proceed as directed in Identification test A under Metaproterenol Sulfate Inhalation Solution, beginning with “Allow the spots to dry”:
to:
Allow the spots to dry, and develop the chromatogram in a solvent system consisting… Read More
MESO-ZEAXANTHIN PREPARATION IDENTIFICATION/C. USPNF Online Online 1-Feb-2023 NA NA Change
(3R,3′S-meso)-zeaxanthin
to:
(3R,3′S)-zeaxanthin
MESO-ZEAXANTHIN COMPOSITION/Stereoisomeric Composition USPNF Online Online 1-Jun-2023 NA NA In System suitability: Change
[Note—The approximate relative retention times for (3S,3′S)-zeaxanthin, (3R,3′S-meso)-zeaxanthin, (3R,3′R)-zeaxanthin, and (3R,3′R,6′R)-lutein are 0.94… Read More
POTASSIUM GLUCONATE ORAL SOLUTION SPECIFIC TESTS USPNF Online Online 1-Feb-2023 NA NA Change
Alcohol Determination 〈611〉, Method II—Distillation Method:
to:
Alcohol Determination 〈611〉, Method I—Distillation Method:
Methyl Acetate CHEMICAL INFORMATION USPNF Online Online 1-Feb-2023 NA NA Change
CAS RN®: 74-20-9.
to:
CAS RN®: 79-20-9.
MESO-ZEAXANTHIN CHEMICAL INFORMATION USPNF Online Online 1-Jun-2023 NA NA Change
(3R,3′S-meso)-Zeaxanthin
to:
(3R,3′S)-Zeaxanthin
AZTEC MARIGOLD ZEAXANTHIN EXTRACT COMPOSITION/Procedure 4: Stereoisomeric Composition USPNF Online Online 1-Feb-2023 NA NA In System suitability/Suitability requirements/Resolution: Change
(3R,3′S meso)-zeaxanthin
to:
(3R,3′S)-zeaxanthin
AND
In Analysis: Change
(3R,3′S Read More
ISOBUTYL ALCOHOL ASSAY/Procedure USPNF Online Online 1-Feb-2023 NA NA In Analysis: Change
rS = sum of all the peaks except those each of which with an area less than 0.1 times the area of the major peak from the Reference solution
to:
rT = sum of all the peaks except those… Read More
FLUTICASONE PROPIONATE NASAL SPRAY IMPURITIES/Organic Impurities USPNF Online Online 1-Feb-2023 NA NA In Analysis: Change
Samples: System suitability solution, Identification solution, and Sample solution
to:
Samples: Identification solution and Sample solution
MESO-ZEAXANTHIN PREPARATION COMPOSITION/Stereoisomeric Composition USPNF Online Online 1-Feb-2023 NA NA In System suitability: Change
[Note—The approximate relative retention times for (3S,3′S)-zeaxanthin, (3R,3′S-meso)-zeaxanthin, (3R,3′R)-zeaxanthin, and (3R,3′R,6′R)-lutein are 0.94… Read More
MESO-ZEAXANTHIN ADDITIONAL REQUIREMENTS/USP Reference Standards <11> USPNF Online Online 1-Jun-2023 NA NA In USP meso-Zeaxanthin RS: Change
(3R,3′S-meso)-Zeaxanthin.
to:
(3R,3′S)-Zeaxanthin.
<251> LEAD PROCEDURES/Procedure 1: Chemical Method USPNF Online Online 1-Jun-2023 NA NA In Analysis: Change
Add to the acid solution 5.0 mL of Standard dithizone solution and 4 mL of Ammonia cyanide solution,
to:
Add to the acid solution 5.0 mL of Standard dithizone solution and 4 mL of Ammonium cyanide… Read More
METARAMINOL BITARTRATE SPECIFIC TESTS/Content of Tartaric Acid USPNF Online Online 1-Feb-2023 NA NA In Analysis: Change
Result = {[(VSVB) × N × F]/2 × W} × 100
to:
Result = {[(VSVB) × N × F]/(2 × W)} × 100
MESO-ZEAXANTHIN IDENTIFICATION/C. USPNF Online Online 1-Jun-2023 NA NA Change
(3R,3′S-meso)-zeaxanthin
to:
(3R,3′S)-zeaxanthin
CHLOROPROCAINE HYDROCHLORIDE INJECTION ASSAY/Procedure USPNF Online Online 1-Feb-2023 NA NA In Sample solution: Change
Transfer about 100 mg of chloroprocaine hydrochloride to a 100-mL volumetric flask, dissolve in 40 mL of methanol, and dilute with water to volume.
to:
Transfer a volume of Injection, equivalent to about 100 mg of… Read More
POLYETHYLENE GLYCOL STANDARDS WITH MOLECULAR WEIGHTS OF 1000, 2000, 3000, 4000, AND 6000 DALTONS (G/MOL) CHEMICAL INFORMATION USPNF Online Online 1-Feb-2023 NA NA Change
CAS RN®: 25332-68-3.
to:
CAS RN®: 25322-68-3.
DEXAMETHASONE SODIUM PHOSPHATE INJECTION ASSAY/Procedure USPNF Online Online 1-Feb-2023 NA NA In Analysis: Change
Result = (rU/rS) × (CS/CU) × (Mr1/Mr22) × 100
to:
Result = (rU/r… Read More
MESO-ZEAXANTHIN PREPARATION ADDITIONAL REQUIREMENTS/USP Reference Standards <11> USPNF Online Online 1-Feb-2023 NA NA In USP meso-Zeaxanthin RS: Change
(3R,3′S-meso)-Zeaxanthin.
to:
(3R,3′S)-Zeaxanthin.
AZTEC MARIGOLD ZEAXANTHIN EXTRACT IDENTIFICATION/C. USPNF Online Online 1-Feb-2023 NA NA Change
(3R,3′S meso)-zeaxanthin
to:
(3R,3′S)-zeaxanthin
<251> LEAD REQUIREMENTS FOR PROCEDURE VALIDATION USPNF Online Online 1-Jun-2023 NA NA Change
• Precision Repeatability
to:
• Precision
METARAMINOL BITARTRATE ADDITIONAL REQUIREMENTS/USP Reference Standards 〈11〉 USPNF Online Online 1-Feb-2023 NA NA In USP Metaraminol Enantiomer RS: Change
3-[(1S,2R)-2-Amino-1-hydroxypropyl]phenol.
C9H13NO2 167.21
to:
3-[(1S,2R)-2-Amino-1-hydroxypropyl]phenol D-tartrate.
C9H Read More